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RNA-Seq of rabbits treated with normal diet or high cholesterol diet

ABSTRACT: RNA-Seq of rabbits treated with normal diet or high cholesterol diet

PROVIDER: PRJNA735787 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR14752131_1.fastq.gz	Fastqsanger.gz
	SRR14752131_2.fastq.gz	Fastqsanger.gz
	SRR14752132_1.fastq.gz	Fastqsanger.gz
	SRR14752132_2.fastq.gz	Fastqsanger.gz
	SRR14752133_1.fastq.gz	Fastqsanger.gz

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RNA-Seq of rabbits treated with normal diet or high cholesterol diet

Project description:We fed PGC1-alpha (mouse gene) transgenic rabbits and control rabits with normal diet or high cholesterol diet. Then we extract RNA from their vascular cells and performed RNA-Seq comapre the expression level of the mRNAs.

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Project description:The aim of the experiment was the analysis of hypercholesterolemia-induced myocardial microRNA alterations. Microarray analysis was applied to assess the expression changes resulted cholesterol-enriched diet. Male Wistar rats were fed with 2% cholesterol/0.25% cholate-enriched or standard diet for 12 weeks. microRNA of heart samples (n = 6) from both high cholesterol and normal diet groups were analysed.

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