Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Spatiotemporal transcriptomes of mouse embryo

ABSTRACT: Spatiotemporal transcriptomes of mouse embryo

PROVIDER: PRJNA739756 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14873679_1.fastq.gz	Fastqsanger.gz
	SRR14873679_2.fastq.gz	Fastqsanger.gz
	SRR14873680_1.fastq.gz	Fastqsanger.gz
	SRR14873680_2.fastq.gz	Fastqsanger.gz
	SRR14873681_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Spatiotemporal transcriptomes of orchid flowers

Project description:Spatiotemporal transcriptomes of orchid flowers

| PRJNA813957 | ENA

Spatiotemporal transcriptomes of mouse embryo

Project description:We performed spatial transcriptome sequencing of mouse embryos to provide spatial cell atlas of mouse organogenesis.

2023-02-19 | GSE178636 | GEO

Developing mouse embryo

Project description:Developing mouse embryo

| PRJNA888039 | ENA

Mouse Transcriptomes

Project description:Mouse Transcriptomes

| PRJEB2494 | ENA

Intermittent fasting alters the spatiotemporal atlas of transcriptomes

Project description:Intermittent fasting alters the spatiotemporal atlas of transcriptomes

| PRJNA647470 | ENA

Expression data from mouse embryo

Project description:Expression data from mouse embryo

| PRJNA1148034 | ENA

Time course expression data from early Bovine embryo, Human embryo, and Mouse embryo

Project description:Time course expression data from early Bovine embryo, Human embryo, and Mouse embryo

| PRJNA117925 | ENA

Spatiotemporal transcriptome of the mouse dentate gyrus

Project description:Spatiotemporal transcriptome of the mouse dentate gyrus

| PRJNA439378 | ENA

Dynamic landscape of enhancer-derived RNA during mouse early embryo development

Project description:Enhancer RNAs (eRNAs) play critical roles in diverse biological processes by mediating the activation of their target genes. However, the systematic landscape and potential regulations and functions of eRNAs during mammalian early embryo development remains elusive. Here, we present the comprehensive detection and characterization of eRNAs during mouse early embryo development. We demonstrated the spatiotemporal and allelic landscape of eRNA expression. We found the asymmetric activation of paternal-specific eRNAs during zygotic genome activation (ZGA). We identified TFs and their cooperation in regulating dynamic eRNA expression. eRNA are involved in multiple developmental signaling pathways through putatively regulating their target genes. Interestingly, we observed that the transcriptions of enhancers themselves are also widely modulated by eRNAs during mouse early embryo development. Critically, we de novo identified a novel eRNA transcribed from a super-enhancer region exclusively expressed at 2-cell stage of mouse early embryos and experimentally validated its key functional role in regulating ZGA and early embryo development.

2024-02-27 | GSE213211 | GEO

Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation

Project description:Anterior mesoderm (AM) and definitive endoderm (DE) progenitors represent the earliest embryonic cell types that are specified during germ layer formation at the primitive streak (PS) of the mouse embryo. Genetic experiments indicate that both lineages segregate from Eomes expressing progenitors in response to different NODAL signaling levels. However, the precise spatiotemporal pattern of the emergence of these cell types and molecular details of lineage segregation remain unexplored. We combined genetic fate labeling and imaging approaches with single cell RNA sequencing (scRNA-seq) to follow the transcriptional identities and define lineage trajectories of Eomes dependent cell types. Accordingly, all cells moving through the PS during the first day of gastrulation express Eomes AM and DE specification occurs before cells leave the PS from Eomes positive progenitors in a distinct spatiotemporal pattern. ScRNA-seq analysis further suggest the immediate and complete separation of AM and DE lineages from Eomes expressing cells as last common bipotential progenitor.

2020-12-07 | GSE151824 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data