Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Aster lavandulifolius

ABSTRACT: Aster lavandulifolius Genome sequencing and assembly

PROVIDER: PRJNA744711 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR15276514_1.fastq.gz	Fastqsanger.gz
	SRR15276514_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Aster altaicus

Project description:Aster altaicus Genome sequencing and assembly

| PRJNA905941 | ENA

Aster souliei

Project description:Aster souliei Genome sequencing

| PRJNA765149 | ENA

Aster tataricus

Project description:Aster tataricus Genome sequencing

| PRJNA482224 | ENA

Aster tongolensis

Project description:Aster tongolensis Genome sequencing

| PRJNA765189 | ENA

Aster fanjingshanicus

Project description:Aster fanjingshanicus Genome sequencing

| PRJNA862274 | ENA

Cooperation between ASTER-dependent nonvesicular transport and NPC1L1 facilitates dietary cholesterol uptake

Project description:Intestinal cholesterol absorption is an important determinant of systemic cholesterol homeostasis. Niemann-Pick C1 Like 1 (NPC1L1), the target of the drug ezetimibe, is a critical player in dietary cholesterol uptake. But how cholesterol moves within the cell downstream of NPC1L1 is unknown. Here we show that the nonvesicular sterol transporters Aster-B and -C cooperate with NPC1L1 to deliver dietary cholesterol from the gut lumen to the enterocyte ER for chylomicron packaging. Aster proteins are recruited to the enterocyte plasma membrane (PM) in response to NPC1L1-dependent cholesterol accumulation. Mice lacking Asters in intestine have impaired cholesterol absorption, and reduced plasma cholesterol. NanoSIMS imaging and tracer studies reveal delayed lipid trafficking into chylomicrons in Aster-deficient enterocytes. Interestingly, in addition to potently blocking NPC1L1, ezetimibe is also a low-affinity inhibitor of Aster-B and -C but not -A, and the structure of the Aster-C-ezetimibe complex reveals the basis for this selectivity. Our findings support a model in which NPC1L1 enriches dietary cholesterol at the apical PM, and ASTERs subsequently traffic this cholesterol to the ER. The findings identify the enterocyte Aster pathway as potential target for treatment of hypercholesterolemia. Alessandra Ferrari, PhD

2023-12-21 | GSE206780 | GEO

Aster

Project description:Transcriptomes of Aster savatieri and Aster savatieri var. pygmaeus (Asteraceae)

| PRJDB3246 | ENA

Thalassianthus aster

Project description:Thalassianthus aster

| PRJNA1138224 | ENA

Small RNA profiling of aster yellows infected Catharanthus roseus plants

Project description:Aster yellows phytoplasma strain Hyd35 (16SrI-B) in micropropagated periwinkle shoots in collection was used to produce infected plants in pots that were separated according to the diverse symptomatology i.e. phyllody and witches’ broom. Small RNA high-throughput sequencing (HTS) was then used to determine the small RNA pattern of these plants. Bioinformatics analysis revealed the presence of expression changes of different miRNA classes and the presence of phytoplasma derived small RNAs. These results could complement previous studies and serve as a starting point for small RNA omics in phytoplasma research

2023-08-11 | GSE213754 | GEO

Aster tataricus

Project description:Aster tataricus overview

| PRJNA482486 | ENA