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ABSTRACT: Duper is a null mutation of Cryptochrome 1 in Syrian hamsters

PROVIDER: PRJNA754138 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR15427056_1.fastq.gz	Fastqsanger.gz
	SRR15427056_2.fastq.gz	Fastqsanger.gz
	SRR15427058_1.fastq.gz	Fastqsanger.gz
	SRR15427058_2.fastq.gz	Fastqsanger.gz
	SRR15427060_1.fastq.gz	Fastqsanger.gz

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Duper is a Cryptochrome 1 null mutation in Syrian hamsters

Project description:Duper is a Cryptochrome 1 null mutation in Syrian hamsters

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Duper is a Cryptochrome 1 null mutation in Syrian hamsters

Project description:The duper mutation is a recessive mutation that shortens the period length of the circadian rhythm in Syrian hamsters. These animals show a large phase shift when responding to light pulses. Using two distinct ecotypes and a fast homozygosity mapping strategy, we identified duper as an early nonsense allele of Cryptochrome 1 (Cry1) leading to a short, unstable protein.

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Changes in the gene expression in the inferior colliculus of the sound stimulated both control Syrian hamsters and the strain GASH:Sal.

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