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Pseudomonas aeruginosa

ABSTRACT: Pseudonomas aeruginosa Bloodstream Infections

PROVIDER: PRJNA756114 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	JAIQJO01.dat.gz	Other
	JAIQJO01.fasta.gz	Fasta.gz
	JAIQJO01.master.dat	Other
	JAIQJP01.dat.gz	Other

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Pseudomonas aeruginosa

Project description:Pseudomonas aeruginosa bloodstream isolate sequencing

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Pseudomonas aeruginosa gene regulation by Staphylococcus aureus exoproducts

Project description:Pseudomonas aeruginosa and Staphylococcus aureus are often co-isolated in persistent infections. The goal of this study was to determine how secreted products from S. aureus affect gene expression in P. aeruginosa. Therefore, media control or S. aureus supernatant was added to P. aeruginosa cultures at 25% total volume and gene expression was measured at 20 min, 1 h, and 2 h using RNA-seq. Overall, after addition of S. aureus supernatant, there was an upregulation in genes involved in metal deprivation and intermediate metabolite uptake.

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Pseudomonas aeruginosa gene regulation by Staphylococcus aureus supernatant or added secreted products

Project description:Pseudomonas aeruginosa and Staphylococcus aureus are often co-isolated in persistent infections. The goal of this study was to determine how secreted products that were identified in S. aureus supernatant affect gene expression in P. aeruginosa. Therefore, media control, the indicated products in media, or S. aureus supernatant was added to P. aeruginosa cultures at 25% total volume and gene expression was measured at 20 min and 2 h using RNA-seq. The individual products induced distinct pathways in P. aeruginosa. The products in combination recapitulated much of the differential gene expression seen in P. aeruginosa in response to S. aureus supernatant.

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DNA Methyltransferase M.PaeTBCFI in a chronically adapted Pseudomonas aeruginosa strain

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Regulatory network underlying the adaptive physiology of Pseudomonas aeruginosa under urinary tract-like conditions

Project description:Pseudomonas aeruginosa is one of the most frequent pathogen dominant in complicated urinary tract infections (UTI). To unravel the adaptation strategies of P. aeruginosa to the conditions in the urinary tract and to define the underlying regulatory network an artificial growth system mimicking the conditions in the urinary tract was established. Transcriptome analyses were used to investigate the physiological status of P. aeruginosa under this conditions.

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