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Bulk RNAseq of AB1-HA murine mesothelioma tumors from immunocompetent or CD4+ T cell depleted mice.

ABSTRACT: Bulk RNAseq of AB1-HA murine mesothelioma tumors from immunocompetent or CD4+ T cell depleted mice.

PROVIDER: PRJNA756568 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR15540910_1.fastq.gz	Fastqsanger.gz
	SRR15540910_2.fastq.gz	Fastqsanger.gz
	SRR15540911_1.fastq.gz	Fastqsanger.gz
	SRR15540911_2.fastq.gz	Fastqsanger.gz
	SRR15540912_1.fastq.gz	Fastqsanger.gz

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Project description:Balb/c mice were inoculated subcutaneously with AB1-HA cells on both flanks on day 0. The mice were then treated with anti-CTLA-4 on day 5 or 6. 7 days later, one tumor was removed for gene expression studies, and the other was left in situ to monitor tumor growth and determine if the eventual outcome was progression or regression. The study design consisted of three experimental groups; (i) untreated mice; (ii) anti-CTLA-4 treated responders; (iii) anti-CTLA-4 treated nonresponders. There were 10 animals in each group.

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