Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Generation of thyroid follicular cell organoids from adult thyroid tissue [mouse]

ABSTRACT: Generation of thyroid follicular cell organoids from adult thyroid tissue [mouse]

PROVIDER: PRJNA762538 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR15858744_1.fastq.gz	Fastqsanger.gz
	SRR15858744_2.fastq.gz	Fastqsanger.gz
	SRR15858745_1.fastq.gz	Fastqsanger.gz
	SRR15858745_2.fastq.gz	Fastqsanger.gz
	SRR15858746_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 44

Similar Datasets

Generation of thyroid follicular cell organoids from adult thyroid tissue

Project description:Generation of thyroid follicular cell organoids from adult thyroid tissue

| PRJNA762536 | ENA

Generation of thyroid follicular cell organoids from adult thyroid tissue [Human]

Project description:Generation of thyroid follicular cell organoids from adult thyroid tissue [Human]

| PRJNA762537 | ENA

Generation of thyroid follicular cell organoids from adult thyroid tissue [Human]

Project description:The thyroid maintains systemic homeostasis by regulating serum thyroid hormone concentrations. Here we report the establishment of adult stem cell-derived three-dimensional (3D) organoids representing murine and human thyroid follicular cells (TFCs). The TFC organoids (TFCO) harbour the complete machinery of hormone production as visualised by the presence of colloid in the lumen and by the presence of essential transporters and enzymes in the polarised epithelial cells that surround a central lumen. Both the established murine as human thyroid organoids express canonical thyroid markers PAX8 and NKX2.1, while the thyroid hormone precursor thyroglobulin is expressed at comparable levels to tissue. Single cell RNA sequencing and transmission electron microscopy confirm that TFCOs phenocopy primary thyroid tissue. Thyroid hormones are readily detectable in conditioned medium of human TFCOs.

2021-12-06 | GSE183961 | GEO

Generation of thyroid follicular cell organoids from adult thyroid tissue [mouse]

2021-12-06 | GSE183962 | GEO

Generation of thyroid follicular cell organoids from adult thyroid tissue [Mouse single-cell]

2021-12-06 | GSE183963 | GEO

Generation of thyroid follicular cell organoids from adult thyroid tissue [Mouse single-cell]

Project description:Generation of thyroid follicular cell organoids from adult thyroid tissue [Mouse single-cell]

| PRJNA762539 | ENA

Comparison of gene expression between follicular thyroid adenoma and follicular thyroid carcinoma

Project description:Follicular thyroid tumours were investigated using global gene expression analysis. Aim of this study was the identification of new markers for follicular thyroid carcinoma. Keywords: cell type comparison Gene expression analysis of 4 follicular thyroid adenomas, 4 follicular thyroid carcinomas, and 4 microinvasive follicular thyroid carcinomas.

2009-02-27 | E-GEOD-15045 | biostudies-arrayexpress

Transcription profiling of radiation-induced follicular thyroid adenomas with sporadic follicular thyroid adenomas

Project description:transcriptome comparison of radiation-induced follicular thyroid adenomas with sporadic follicular thyroid adenomas

2005-11-04 | E-MEXP-484 | biostudies-arrayexpress

miRNA high-throughput sequencing of follicular thyroid tumors

Project description:We report data obtaibed from high-throughput sequencing of small RNAs in 20 samples of follicular thyroid tumors. We analyzed a total of 4.7±1.5million reads per sample with 3 different pipelines. The main goal was to evaluate the usefulness of next generation sequencing in small RNA profiling and the concordance of its results with microarrays and qPCR. Additionally we verified published follicular thyroid tumor biomarkers in the set of our samples. Small RNA expression profiling with High Throughput Sequencing of 20 thyroid tumor samples, performed on an Illumina HiScan-SQ.

2014-03-07 | E-GEOD-39112 | biostudies-arrayexpress

Comparison of gene expression between follicular thyroid adenoma and follicular thyroid carcinoma

2009-02-28 | GSE15045 | GEO