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Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days

ABSTRACT: Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days

PROVIDER: PRJNA768800 | ENA |

REPOSITORIES: ENA

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Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days [Colon]

Project description:MBELN isolated mulberry bark purified by sucrose gradient were orally gavaged to B6 mice for 7 days once in a day at aconcentration of 10 x 10E+09 particle/100 µl. After 7 days, colon tissue were harvested. RNA was isolated and sent to invitorgen for Affymetrix array. The purpose of the experiment was to see which set of genes go up or down after MBELN treatment and their link to gut homeostasis.

2021-10-07 | GSE185351 | GEO

Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days [Crypt]

Project description:MBELN isolated mulberry bark purified by sucrose gradient were orally gavaged to B6 mice for 7 days once in a day at aconcentration of 10 x 10E+09 particle/100 µl. After 7 days, colon specific crypt cells were isolated. RNA was isolated and sent to invitorgen for Affymetrix array. The purpose of the experiment was to see which set of genes go up or down after MBELN treatment and their link to gut homeostasis.

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Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days [Colon]

Project description:Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days [Colon]

| PRJNA768805 | ENA

Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days [Crypt]

Project description:Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days [Crypt]

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Mulberry, an edible plant, bark derived exosomes-like nanoparticles (MBELN) treatment of B6 mice for 7 days

Project description:This SuperSeries is composed of the SubSeries listed below.

2021-10-07 | GSE185352 | GEO

Identification of Exosome-Like Nanoparticle Derived MicroRNAs from Eleven Edible Plants

Project description:In this study, we found that the highly expressed miRNAs appear in EPDELNs (Edible plant-derived exosome-like nanoparticles) have the potential to regulate human mRNA in a cross-kingdom manner. Target prediction and functional analysis revealed that highly expressed miRNAs were closely associated with inflammatory responses and cancer-related pathways. Therefore, we hypothesized that miRNAs in EPDELNs may be a crucial factor behind the regulatory function of EPDELNs.

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