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Hnrnpk is essential for embryonic limb bud development as a transcription activator and insulator collaborator

ABSTRACT: Hnrnpk is essential for embryonic limb bud development as a transcription activator and insulator collaborator

PROVIDER: PRJNA773754 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR16537375_1.fastq.gz	Fastqsanger.gz
	SRR16537375_2.fastq.gz	Fastqsanger.gz
	SRR16537376_1.fastq.gz	Fastqsanger.gz
	SRR16537376_2.fastq.gz	Fastqsanger.gz
	SRR16537377_1.fastq.gz	Fastqsanger.gz

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Hnrnpk is essential for embryonic limb bud development as a transcription activator and insulator collaborator

Project description:Proper development of limb bud relies on the concordance of various signals, otherwise limb deformities occur. We report that heterogeneous nuclear ribonucleoprotein K (hnRNPK) is essential for limb bud development. here, we knock out Hnrnpk in limb bud and exert the RNA-seq, ATAC-seq, CUT&RUN-seq, and Hi-C assay using primary limb bud cells to explore the function of Hnrnpk in limb bud development.

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