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Comparison of toxicological effects and exposure levels between triclosan and its structurally similar chemicals using in vitro tests for read-across case study

ABSTRACT: Comparison of toxicological effects and exposure levels between triclosan and its structurally similar chemicals using in vitro tests for read-across case study

PROVIDER: PRJNA774988 | ENA |

REPOSITORIES: ENA

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Comparison of toxicological effects and exposure levels between triclosan and its structurally similar chemicals using in vitro tests for read-across case study

Project description:To improve prediction accuracy of read-across, we compared biological similarities between triclosan and its structurally similar chemicals including diclosan and 1-chloro-3-(4-chlorophenoxy) benzene. To elucidate and compare the potential mechanisms between them, we performed in vitro toxicogenomics with rat primary hepatocytes.

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