Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Panagrolaimus kolymaensis isolate:S50751

ABSTRACT: Panagrolaimus kolymaensis isolate:S50751 Genome sequencing and assembly

PROVIDER: PRJNA786727 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR17159947_subreads.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Panagrolaimus davidi

Project description:Panagrolaimus davidi Genome sequencing

| PRJNA245862 | ENA

Panagrolaimus

Project description:Panagrolaimus sp. overview

| PRJNA917375 | ENA

Panagrolaimus davidi

Project description:Panagrolaimus davidi overview

| PRJNA258298 | ENA

Panagrolaimus superbus

Project description:Panagrolaimus superbus overview

| PRJNA1111219 | ENA

Panagrolaimus detritophagus

Project description:Panagrolaimus detritophagus overview

| PRJNA1125109 | ENA

Panagrolaimus davidi strain:CB1

Project description:Panagrolaimus davidi strain:CB1 Transcriptome or Gene expression

| PRJNA247454 | ENA

Transcriptional response of an azole-resistant Candida parapsilosis isolate [voriconazole].

Project description:Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of voriconazole. Whole genome microarrays were used to compare the transcriptional response of the voriconizole-resistant and susceptible isolates.

2011-04-18 | GSE27408 | GEO

Transcriptional response of an azole-resistant Candida parapsilosis isolate [posaconazole].

Project description:Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of posaconazole. Whole genome microarrays were used to compare the transcriptional response of the posaconazole-resistant and susceptible isolates.

2011-04-18 | GSE27407 | GEO

Transcriptional response of an azole-resistant Candida parapsilosis isolate [fluconazole].

Project description:Azole resistance was induced in vitro by growth of a susceptible C. parapsilosis isolate in the presence of fluconazole. Whole genome microarrays were used to compare the transcriptional response of the fluconazole-resistant and susceptible isolates.

2011-04-18 | GSE27405 | GEO

Loss of sterol demethylase activity reduces both azole and echinocandin antifungal susceptibility in a clinical isolate of C. parapsilosis

Project description:The present study describes a novel mechanism of antifungal resistance affecting the susceptibility of both the azole and echinocandin antifungals in an azole-resistant isolate from a matched pair of C. parapsilosis isolates obtained from a patient with prosthetic valve endocarditis. Transcriptome analysis indicated differential expression of several genes in the resistant isolate including upregulation of ERG1, ERG2, ERG5, ERG6, ERG11, ERG24, ERG25, ERG27, DAP1 and UPC2, of the ergosterol biosynthesis pathway. Whole genome sequencing revealed a mutation in the ERG3 gene leading to a G111R amino acid substitution in the resistant isolate. Subsequent introduction of this allele in the native ERG3 locus in the susceptible isolate resulted in a fluconazole MIC of >64 mg/ml and a caspofungin MIC of 8 mg/ml. Corresponding allelic replacement of the wildtype allele for the mutant allele in the resistant isolate resulted in a drop in MIC to 1 mg/ml for both fluconazole and caspofungin. Sterol profiles indicated a loss of sterol demethylase activity as a result of this mutation. This work demonstrate that this G111R mutation is wholly responsible for the resistant phenotype in the C. parapsilosis resistant isolate and is the first report of this multidrug resistance mechanism.

2017-05-25 | GSE98986 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data