Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Porphyromonas gingivalis tyrosine kinase is a fitness determinant in polymicrobial infections

ABSTRACT: Porphyromonas gingivalis tyrosine kinase is a fitness determinant in polymicrobial infections

PROVIDER: PRJNA788126 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR17205164.fastq.gz	Fastqsanger.gz
	SRR17205165.fastq.gz	Fastqsanger.gz
	SRR17205166.fastq.gz	Fastqsanger.gz
	SRR17205167.fastq.gz	Fastqsanger.gz
	SRR17205168.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 20

Similar Datasets

Characterization of a bacterial tyrosine kinase in Porphyromonas gingivalis involved in polymicrobial synergy

Project description:RNA-Seq of wild-type Porphyromonas gingivalis compared to ΔPGN_1524 mutant Illumina based RNA-Seq was used to probe transcriptome differences between wild-type Porphyromonas gingivalis and ΔPGN_1524 mutant

2014-07-19 | E-GEOD-55192 | biostudies-arrayexpress

Characterization of a bacterial tyrosine kinase in Porphyromonas gingivalis involved in polymicrobial synergy

Project description:RNA-Seq of wild-type Porphyromonas gingivalis compared to ΔPGN_1524 mutant

2014-07-19 | GSE55192 | GEO

Porphyromonas gingivalis tyrosine kinase is a fitness determinant in polymicrobial infections

Project description:Tn-Seq was used to identify P. gingivalis genes that confer fitness during cooperative growth with S. gordonii or F. nucleatum in a murine abscess model.

2022-04-28 | GSE190703 | GEO

Porphyromonas gingivalis ATCC 33277

Project description:Characterization of a bacterial tyrosine kinase in Porphyromonas gingivalis involved in polymicrobial synergy

| PRJNA238868 | ENA

Role of PG1626 in Porphyromonas gingivalis ATCC33277

Project description:Wild type Porphyromonas gingivalis strain ATCC33277 (V3176) and PG1626 - deficient mutant (V3177) were grown in iron replete conditions was used to compare to Porphyromonas gingivalis strains grown in iron chelated conditions.

2023-06-08 | GSE174493 | GEO

Porphyromonas gingivalis gene expression during co-culture with Treponema denticola

Project description:Porphyromonas gingivalis and Treponema denticola are periodontalpathogens that are associated with the severity and progression of periodontal diseases. This study investigates the gene expression of Porphyromonas gingivalis during co-culture with Treponema denticola

2014-03-31 | E-MTAB-2214 | biostudies-arrayexpress

Treponema denticola gene expression during co-culture with Porphyromonas gingivalis

Project description:Porphyromonas gingivalis and Treponema denticola are periodontalpathogens that are associated with the severity and progression of periodontal diseases. this study investigates the gene expression of Treponema denticola during co-culture with Porphyromonas gingivalis.

2014-03-31 | E-MTAB-2257 | biostudies-arrayexpress

Porphyromonas gingivalis Tyrosine Kinase Is a Fitness Determinant in Polymicrobial Infections.

Project description:Many pathogenic microbial ecosystems are polymicrobial, and community function can be shaped by interbacterial interactions. Little is known, however, regarding the genetic determinants required for fitness in heterotypic community environments. In periodontal diseases, Porphyromonas gingivalis is a primary pathogen, but only within polymicrobial communities. Here, we used a transposon sequencing (Tn-Seq) library of P. gingivalis to screen for genes that influence fitness of the organism in a coinfection murine abscess model with the oral partner species Streptococcus gordonii and Fusobacterium nucleatum. Genes impacting fitness with either organism were involved in diverse processes, including metabolism and energy production, along with cell wall and membrane biogenesis. Despite the overall similarity of function, the majority of identified genes were specific to the partner species, indicating that synergistic mechanisms of P. gingivalis vary to a large extent according to community composition. Only two genes were identified as essential for P. gingivalis fitness in abscess development with both S. gordonii and F. nucleatum: ptk1, encoding a tyrosine kinase, and inlJ, encoding an internalin family surface protein. Ptk1, but not InlJ, is required for community development with S. gordonii, and we found that the action of this kinase is similarly required for P. gingivalis to accumulate in a community with F. nucleatum. A limited number of P. gingivalis genes are therefore required for species-independent synergy, and the Ptk1 tyrosine kinase network may integrate and coordinate input from multiple organisms.

| S-EPMC9202411 | biostudies-literature

Role of RNA-binding protein, Pgr, in Porphyromonas gingivalis

Project description:Role of RNA-binding protein, Pgr, in Porphyromonas gingivalis.

2022-10-08 | GSE168570 | GEO