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RNA-sequencing analysis of mouse epithelial NMuMG cells with Cas9 or UGCG knock out

ABSTRACT: RNA-sequencing analysis of mouse epithelial NMuMG cells with Cas9 or UGCG knock out

PROVIDER: PRJNA792612 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR17338262.fastq.gz	Fastqsanger.gz
	SRR17338263.fastq.gz	Fastqsanger.gz
	SRR17338264.fastq.gz	Fastqsanger.gz
	SRR17338265.fastq.gz	Fastqsanger.gz
	SRR17338266.fastq.gz	Fastqsanger.gz

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RNA-sequencing analysis of mouse epithelial NMuMG cells with Cas9 or UGCG knock out

Project description:We report the gene expression in mouse NMuMG cells with or without UGCG depletion using RNA sequencing. After data analysis, the 11218 transcripts were identified. Among these transcripts, the TGF-β signaling target genes and EMT marker genes were significantly upregulated in UGCG depleted NMuMG cells. Then we used these genes and mouse TGF-β or EMT gene signatures to do the gene set enrichment analysis and showed the negative correlation of UGCG and TGF-β signaling or EMT in NMuMG cells.

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