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Differentially expressed genes between YY1 knockdown and control cells, transfected in colorectal cancer cell line DLD-1

ABSTRACT: Differentially expressed genes between YY1 knockdown and control cells, transfected in colorectal cancer cell line DLD-1

PROVIDER: PRJNA798456 | ENA |

REPOSITORIES: ENA

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Differentially expressed genes between YY1 knockdown and control cells, transfected in colorectal cancer cell line DLD-1

Project description:Yin Yang 1 (YY1) is a multifunctional transcription factor with critical roles in carcinogenesis and metastasis. However, its biological role and clinical impact in colorectal cancer (CRC) remain unclear. This study aimed to elucidate the oncological role of YY1 in CRC. To indentify the target genes of YY1, microarray analysis was performed on siYY1 and siControl transfected cells.

2022-01-19 | GSE193948 | GEO

Differentially expressed genes between YY1 knockdown and control cells, transfected in colorectal cancer cell line SW48

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Differentially expressed genes between YY1 knockdown and control cells, transfected in colorectal cancer cell line SW48

Project description:Differentially expressed genes between YY1 knockdown and control cells, transfected in colorectal cancer cell line SW48

| PRJNA798455 | ENA

Expression data from in vitro polarized-pathogenic Th17 system transfected with YY1 shRNA lentivirus

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HMGA2-driven gene expression in human colorectal DLD-1 cells.

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miR-21-5p-driven gene expression in human colorectal DLD-1 cells.

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ChIP-seq of AP4 binding in human colorectal cancer cells DLD-1.

Project description:In order to comprehensively identify genes directly regulated by AP4, a genome-wide chromatin-immunoprecipitation analysis (ChIP) followed by next generation sequencing (ChIP-seq) was performed after activation of a conditional AP4 allele in DLD-1 cells. One DLD-1 Sample was sequenced.

2013-05-31 | E-GEOD-46935 | biostudies-arrayexpress

Gene expression profiling of AGS Gastric Cancer cells upon YY1 knock down

Project description:Yin Yang 1 (YY1) is a ubiquitous transcription factor belonging to the GLI-Kruppel class of zinc finger proteins regulating diverse biological processes including cell proliferation, development, DNA damage responses and also involved in carcinogenesis. The protein is involved in repressing and activating a diverse number of promoters.In order to study the role of the transcription factor YY1 in gastric cancer, transcriptome wide gene expression analysis was performed upon silencing the YY1 gene in gastric cancer cell line, AGS using Affymetrix Human Transcriptome 2.0 array. Transcriptome Analysis Console (TAC) Software was used for the analysis of differentially expressed genes between AGS_YY1_siRNA transfected and AGS_NTC_siRNA transfected cells.

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Quantitative profiling of differentially expressed miRNAs in siCTL- and siOASL-transfected HUVECs

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Expression changes in Yy1 knock down mouse embryonic stem cells

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