Project description:Whole Exome Sequencing of cohorts of Mutant Braf mouse model melanoma DNA and germline DNA. The cohorts are (1) Mutant Braf mouse model melanomas, (2) Mutant Braf mouse model melanomas from UVR exposed mice and (3) Mutant Braf mouse model melanomas from UVR exposed, sunscreen protected mice.
Project description:Characterization of the heritability and genetic factors underlying the differential response to antiseizure drugs (ASDs) in a newly developed mouse model of ASD resistance.
Project description:After establishing mouse myopia model, we performed liquid chromatography-tandem mass spectrometry-based proteomic methods to evaluate the mouse retina protein profiles to explore the underlying mechanism.
