Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ATAC-seq comparatively analyse chromatin accessibility varition of control, TNFα and TNFα+JNK I treated GSCs

ABSTRACT: ATAC-seq comparatively analyse chromatin accessibility varition of control, TNFα and TNFα+JNK I treated GSCs

PROVIDER: PRJNA799758 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR17712287_1.fastq.gz	Fastqsanger.gz
	SRR17712287_2.fastq.gz	Fastqsanger.gz
	SRR17712288_1.fastq.gz	Fastqsanger.gz
	SRR17712288_2.fastq.gz	Fastqsanger.gz
	SRR17712289_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

ATAC-seq comparatively analyse chromatin accessibility varition of control, TNFα and TNFα+JNK I treated GSCs

Project description:Among 3,673 TNFα-induced gain of accessibility (at least 2 folds of upregulation in TNFα-treated TPC2-4 cells compared with control), and most of the gained peaks were significantly suppressed by JNKi treatment (TPC2-4 TNFα+JNKi/TPC2-4 TNFα, JNKi: JNK-IN-8, a kinase inhibitor specific for JNK (c-Jun N-terminal kinase) that inhibited phosphorylation of c-JUN)

2022-08-24 | GSE194221 | GEO

Control, TNFα and TNFα+JNK I treated GSCs

Project description:Control, TNFα and TNFα+JNK I treated GSCs

| PRJNA799754 | ENA

Next Generation Sequencing Facilitates Quantitative Analysis of control, TNFα and TNFα+JNK I treated GSCs Transcriptomes

Project description:Among 830 TNFα-induced genes (at least 1.5 folds of upregulation in TNFα-treated TPC2-4 cells compared with control), the expression of 268 genes is significantly suppressed by JNKi treatment (TPC2-4 TNFα+JNKi/TPC2-4 TNFα, JNKi: JNK-IN-8, a kinase inhibitor specific for JNK (c-Jun N-terminal kinase) that inhibited phosphorylation of c-JUN)

2022-08-24 | GSE194220 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of control, TNFα and TNFα+JNK I treated GSCs Transcriptomes

Project description:Next Generation Sequencing Facilitates Quantitative Analysis of control, TNFα and TNFα+JNK I treated GSCs Transcriptomes

| PRJNA799759 | ENA

Control, TNFα and TNFα+JNK I treated GSCs

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-08-24 | GSE194222 | GEO

ATAC-seq of primary mammalian aortic endothelial cells before and after TNFα stimulation

Project description:To identify conserved TNFα-induced changes in chromatin-accessibility in mammals, we performed ATAC-seq in primary vascular endothelial cells (ECs) isolated from the aortas of human (HAEC), mouse (MAEC) and cow (BAEC), before and after TNFα. We overlay our data with multi-species NF-κB binding data and identify multiple modes of NF-κB-chromatin interactions that are conserved during mammalian TNFα response. Our cross-species approach identifies conserved changes in chromatin-accessibility at NF-κB binding sites that are disease-relevant and essential during mammalian acute inflammation.

2020-06-01 | E-MTAB-7878 | biostudies-arrayexpress

RNA-seq of NSC11 GSCs in the olfactory bulb (OB) compared to the right hemisphere (RH)

Project description:RNA-seq analysis of NSC11 GSCs present in the OB compared to the RH to analyse the influence of the brain microenvironment to the tumor cells gene expression.

2022-12-14 | GSE212161 | GEO

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in GBM and GSCs

Project description:Genome-wide DNA methylation and trancription profiling of different subtypes in GBM (TCGA) and glioma stem cells (GSCs) were carried out using Illumina BeadChip HumanMethylation 450K array (450K array) to analyse over 485K CpG sites accross each samples. 450K array data for 94 GBM samples comprising 4 different subtypes i.e. Proneural (PN), Mesenchymal (MES), Classical (CL) and Neural (N) were used for GBM analysis. Similarly, 450K array for 23 GSCs and 1NHA, RNA seq for 29 GSCs and affimetrix microarray gene expression array for 12 GSCs were used for GBM data analyses.

2017-11-22 | GSE90498 | GEO

Transcriptome expression pattern of E11.5 PGCs, P2 GSCs, and CD49f+GSCs.

Project description:The cell identities of CD49f+GSCs were further identified by comparing them with the E11.5 PGCs and P2 GSCs. The transcriptomic analysis revealed that the CD49f+GSCs had 1/3 similar genes profile to the E11.5 PGCs and P2 GSCs. Further gene ontology (GO) analysis demonstrated that the E11.5 PGCs, P2 GSCs, and CD49f+GSCs shared the partial similar gene expression profile of pluripotency regulation signaling pathway, PI3K-AKT signaling, chemokine signaling, and HIF-1 signaling.

2017-11-09 | GSE106664 | GEO

Transcriptome expression pattern of E11.5 PGCs, P2 GSCs, and CD49f+GSCs.

Project description:Transcriptome expression pattern of E11.5 PGCs, P2 GSCs, and CD49f+GSCs.

| PRJNA417561 | ENA