Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: RNA-seq of tame and aggressive fox Hypothalamus

PROVIDER: PRJNA802593 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR17848418.fastq.gz	Fastqsanger.gz
	SRR17848419.fastq.gz	Fastqsanger.gz
	SRR17848420.fastq.gz	Fastqsanger.gz
	SRR17848421.fastq.gz	Fastqsanger.gz
	SRR17848422.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Project description:RNA-seq of tame and aggressive fox Adrenals

| PRJNA872183 | ENA

Project description:RNA-seq of tame and aggressive fox pituitary

| PRJNA387034 | ENA

Transcriptome responses to selection for tame/aggressive behaviors in silver foxes (Vulpes vulpes)

Project description:Domestication leads to a spectrum of striking behavioral changes whose genetic basis remains largely unknown. Silver foxes have been selectively bred for tame and aggressive behaviors for over 50 years at the Institute for Cytology and Genetics in Novosibirsk, Russia. To further understand the genetic basis and molecular mechanisms underlying tame and aggressive behavioral phenotypes segregating in selected strains of the silver fox, we quantified genome-wide gene expression levels using RNA-seq in two selected brain tissues, right prefrontal cortex and basal forebrain, from 12 aggressive and 12 tame individuals. Expression analysis reveals 146 differentially expressed genes in prefrontal cortex between tame and aggressive individuals at a 5% FDR, and 33 hits were found in basal forebrain. These candidates include genes in key pathways known to be critical to neurological processing, such as serotonin and glutamate receptor pathways. The data relate in interesting ways to neurological and pharmacological effects that are actively being studied to understand human aggression. In addition, we identified 31,000 high quality exonic SNPs, 295 of which show significant allele frequency differences between tame and aggressive individuals at an adjust P-value < 0.05 level from gene dropping simulation based on the entire pedigrees. A non-synonymous change in a glutamate receptor, GRM3, is among these significant SNPs, indicating that expression and allele-frequency changes are hitting the same pathways. These changes in expression level and allele frequency might be the direct response to the artificial selection and will help understand the genetic basis of mammalian domestication process.

2018-05-30 | GSE76517 | GEO

Transcription profiling of silver fox brain selected for tame behavior vs non-selected silver fox

Project description:Comparison of brain gene expression between silver foxes selected for tame behavior and non-selected silver fox.

2005-12-31 | E-MEXP-451 | biostudies-arrayexpress

Project description:RNA-seq assay of aggressive and tame grey rats hypothalamus, hippocampus, midbrain tegmentum and periaqueductal gray

| PRJNA668014 | ENA

rat_brain_mRNASeq

Project description:mRNA Sequencing was done in whole brain hemispheres of the 75 most tame and 75 most aggressive rats of an F2 intercross of rat lines selected for tame and aggressive behavior towards humans. The brain gene expression levels are associated with 1728 genetic markers across the genome to identify expression QTL (eQTL). Genes whose expression is influenced by the same genetic loci that also influence tameness are candidate genes for tame and aggressive behavior. The list of genetic markers can be found in the supplementary materials of the paper for this study. A series of genotype data spreadsheets and associated data processing protocol are available from http://www.ebi.ac.uk/arrayexpress/files/E-MTAB-2544/E-MTAB-2544.additional.1.zip.

2014-08-27 | E-MTAB-2544 | biostudies-arrayexpress

Project description:Resequencing of tame, aggressive and conventional farmed foxes.

| PRJNA376561 | ENA

Vulpes vulpes

Project description:Transcriptome responses to selection for tame/aggressive behaviors in silver foxes (Vulpes vulpes)

| PRJNA307604 | ENA

Nuclear receptor corepressor (NCOR) and HDAC3 in hypothalamus [ChIP-Seq]

Project description:We determined genomic binding of HDAC3 in mouse hypothalamus by ChIP-seq, and identified target genes of the NCOR/HDAC3 complex in hypothalamus of NS-DADm (mutated deacetylase activation domain in NCORs) mice by RNA-seq.

2018-10-29 | GSE92451 | GEO

Diel multi-tissue genome-scale metabolic models of Vitis vinifera

Project description:The first GSSM of V. vinifera was reconstructed (MODEL2408120001). Tissue-specific models for stem, leaf, and berry of the Cabernet Sauvignon cultivar were generated from the original model, through the integration of RNA-Seq data. These models have been merged into diel multi-tissue models to study the interactions between tissues at light and dark phases.

2024-09-02 | MODEL2408160001 | BioModels

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data