Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Iron oxide

PROVIDER: PRJNA805082 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR17968633_1.fastq.gz	Fastqsanger.gz
	SRR17968633_2.fastq.gz	Fastqsanger.gz
	SRR17968634_1.fastq.gz	Fastqsanger.gz
	SRR17968634_2.fastq.gz	Fastqsanger.gz
	SRR17968635_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 126

Similar Datasets

Whole genome analysis of iron oxide nanoparticles treated mensenchymal stem cells

Project description:To determine the cellular effect of iron oxide nanoparticles on MSC, we performed gene expression microarray assay to explore more intensive molecular basis.

2016-04-27 | GSE80695 | GEO

Mechanisms and Novel Proteins for Iron Oxide Mineral Reduction in the Hyperthermophilic Crenarchaeon Pyrodictium delaneyi

Project description:Dissimilatory iron reduction by hyperthermophilic archaea occurs in many geothermal environments and generally relies on microbe-mineral interactions that transform various iron oxide minerals. In this study, the physiology of dissimilatory iron and nitrate reduction was examined in the hyperthermophilic crenarchaeon Pyrodictium delaneyi Su06T. Protein electrophoresis showed that the c-type cytochrome and general protein compositions of P. delaneyi changed when grown on ferrihydrite relative to nitrate. Differential proteomic analyses using tandem mass tagged protein fragments and mass spectrometry detected 660 proteins and differential production of 127 proteins. Among these, two putative membrane-bound molybdopterin-dependent oxidoreductase complexes increased in relative abundance 60- to 3,000-fold and 50-100-fold in cells grown on iron oxide. A putative 8-heme c-type cytochrome was 60-fold more abundant in iron grown cells and was unique to the Pyrodictiaceae. There was also a >14,700-fold increase in a membrane transport protein in iron grown cells. There were no changes in the abundances of flagellin proteins nor a putative nitrate reductase, but a membrane nitric oxide reductase was more abundant on nitrate. These data help to elucidate the mechanisms by which hyperthermophilic crenarchaea generate energy and transfer electrons across the membrane to iron oxide minerals.

2020-12-23 | PXD020757 | Pride

Gene expression of magnetic fluid hyperthermia (MFH) in ovarian cancer cells

Project description:The expression ovarian cancer cell line HeyA8 was studied when the cells were treated with MFH at 43˚C for 30 min, the iron oxide nanoparticles concentration was 0.5 mgFe/ml.

2017-12-01 | GSE92990 | GEO

Interaction of iron oxide nanoparticles with human plasma

Project description:The Interaction of iron oxide nanoparticles with human plasma was studied.

2019-04-11 | PXD004441 | Pride

Profiling axonal transcriptome of mouse hippocampal neurons in response to force

Project description:Magnetically-actuated iron oxide nanoparticles (MNP) have emerged as a technology to chronically expose axons of developing neurons to extremely low mechanical forces. This force was found to induce axon outgrowth. Axon-Seq has been performed to profile local gene expression in response to the stimulus.

2022-03-07 | GSE197808 | GEO

Project description:PFASs removal in iron oxide and FeRB based CWs

| PRJNA786690 | ENA

Transcriptomic study of NR8383 rat macrophages cells following exposure to zinc iron oxide (ZnFe2O4, NRCWE021)

Project description:To identify differentially expressed genes and key biological pathways that define toxicity following nanomaterial exposure, we performed microarray analyses on NR8383 macrophages exposed for 4 h to 17 µg/mL of zinc iron oxide (ZnFe2O4, NRCWE021). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement N°. 686098

2023-08-18 | GSE156659 | GEO

Transcription profiling of rat glomeruli: conventionally-isolated and laser capture microdissected glomeruli

Project description:We compared the gene expression analysis of 2 different glomerular isolation techniques (laser capture microdissection with 2 rounds of RNA amplification and unamplified glomerular RNA after iron perfusion with glomerular sieving) and obtained different results depending on the glomerular isolation technique that was used Experiment Overall Design: Paired kidneys from Lewis-Hsd rat kidneys were collected. The glomeruli of one kidney was obtained by LCM with 2 rounds of RNA amplification while the unamplified glomerular RNA of the contralateral kidney was obtained after perfusion with iron oxide and isolated by magnetic purification and a glomerular sieving technique. The RNA was analyzed using the Affymetrix Rat 230A microarrays.

2008-06-17 | E-GEOD-8998 | biostudies-arrayexpress

hot springs metagenome

Project description:Iron Oxide Mats in Acidic Hot Springs Raw sequence reads

| PRJNA306640 | ENA

Modulation of Pulmonary Toxicity in Metabolic Syndrome due to Variations in Nanoparticle-Biocorona Composition

Project description:Following introduction into a biological environment, nanoparticles (NPs) interact with biomolecules forming a biocorona (BC) on their surface altering cell interactions and toxicity. Metabolic syndrome (MetS) is a prevalent condition and enhances susceptibility to inhaled exposures. We hypothesize distinct NP-biomolecule interactions occur in the lungs due to MetS resulting in the formation of unique NP-BCs contributing to enhanced toxicity. Bronchoalveolar lavage fluid (BALF) was collected from healthy and MetS mouse models and used to evaluate variations in the BC formation on 20 nm iron oxide NPs. NPs without or with BCs were characterized for hydrodynamic size and zeta potential. Protein and lipid components of the BCs were evaluated via proteomic and lipidomic assessments. Unique biomolecules were determined to associate with iron oxide NPs while shared biomolecules demonstrated differential abundance based on disease state. A mouse macrophage cell line was utilized to examine alterations in cell interactions and toxicity due to BCs. Exposures for 1h or 24h with NPs did not demonstrate overt cytotoxicity. Darkfield microscopy and X-ray fluorescence (XRF) analysis determined enhanced iron oxide NP internalization due to the MetS BC compared to the healthy BC. Macrophages exposed to NPs with a MetS-BC for 1h or 24h demonstrated enhanced gene expression of inflammatory markers CCL2, IL-6, and TNF-alpha compared to ion oxide NPs with a healthy BC. Inflammatory pathways were examined by western blots to determine activation of specific proteins within the MAP kinase, Jak-Stat, and NF- kB signaling pathways. Activation of STAT3, NF-kB, and ERK pathways were determined to be upregulated due to the MetS-BC. Specifically, the Jak-Stat pathway was determined to be the most upregulated inflammatory pathway following exposure to NPs with a MetS BC.

2022-04-27 | MSV000089322 | MassIVE

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data