Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Venomics of the Central European Myrmicine Ants Myrmica rubra and Myrmica ruginodis

PROVIDER: PRJNA807911 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18057171_1.fastq.gz	Fastqsanger.gz
	SRR18057171_2.fastq.gz	Fastqsanger.gz
	SRR18057172_1.fastq.gz	Fastqsanger.gz
	SRR18057172_2.fastq.gz	Fastqsanger.gz
	SRR18057173_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Venomics of the Central-European Myrmicine Ants Myrmica rubra and Myrmica ruginodis

Project description:Animal venoms are a rich source of novel biomolecules with tremendous potential in medicine and agriculture. Ants represent one of the most species-rich lineages of venomous animals. However, only a fraction of their biodiversity has been studied so far. Here, we investigated the venom compositions from Myrmica rubra and Myrmica ruginodis, two members of the Myrmicinae subfamily of ants. We applied a proteo-transcriptomics based venomics workflow. Our analysis revealed that venoms of both species are composed of several protein classes, such as venom serine protease, cysteine-rich secretory proteins, antigen 5 and pathogenesis-related 1 proteins (CAP), Kunitz-type serine protease inhibitors or venom acid phosphatase. Several protein classes identified are known venom allergens, and for the first time we detected phospholipase A1 in the venom of M. ruginodis. We also identified two novel toxins of the epidermal growth factor (EGF) family in its venom proteome and an array of additional EGF-like toxins in venom gland transcriptomes of both species. They display similarity to known toxins from the related myrmecine Manica rubida and the Australian red bulldog ant Myrmecia gullosa of the Myrmeciinae subfamily and may serve as nociceptive weapons in defensive scenarios. Our work suggests that the venoms of M. rubra and M. ruginodis contain many high molecular proteins and enzymes with putatively cell damaging functions. Nevertheless, the presence of EGF-like toxins underpins that myrmicine ants also recruited smaller peptide components into their venom arsenal. Although little is known about the bioactivity and function of these EGF-like toxins, their presence in Myrmecinae and Myrmeciinae suggests that they play an important role for the venom systems of Formicoidea. Our work adds to the emerging picture of ant venoms as a source for novel biomolecules. This underlines the importance to incorporate such taxa in future venom bioprospecting programs.

2022-06-09 | PXD033537 | Pride

Peptide diversity of myrmicine ant venoms

Project description:Using integrated transcriptomics and proteomic approaches, we characterized the venom peptidome of six ants representative of the six Myrmicinae tribes : Myrmica ruginodis, Pogonomyrmex californicus, Stenamma debile, Solenopsis saevissima, Daceton armigerum and Tetramorium africanum. We identified a total of 79 myrmicitoxin precursors which can be classified into 38 biochemical families according to their mature sequences. Myrmicine ant venom peptidome exhibited heterogeneous composition.

2024-10-16 | PXD033547 | Pride

The analysis of gene transcription and the effect of drug resistance of Radix Paeoniae Rubra Decoction on Staphylococcus aureus

Project description:To study the effect of Radix Paeoniae Rubra decoction on tolerance of Staphylococcus aureus.The effect of Radix Paeoniae Rubra on the resistance of Staphylococcus aureus to oxacillin sodium was studied by millipore dilution method in this experiment.At the same time ,conducted on transcriptome analysis of Staphylococcus aureus related genes in Radix Paeoniae Rubra.And to detect the expression level of related genes of Staphylococcus aureus under the action of Radix Paeoniae Rubra by PCR technology.The tolerance of Staphylococcus aureus was decreased obviously when the concentration of Radix Paeoniae Rubra decoction was above 1mg/ml.The effect of Radix Paeoniae Rubra decoction on the expression of tolerance genes femB,pvL and gluM when the concentration of Radix Paeoniae Rubra decoction was above 4mg/ml.When rhe concentration of Radix Paeoniae Rubra is more than 1mg/ml,it can effectively reduce the resistance of Staphylococcus aureus to oxacillin sodium.The reason may be due to the effect of Radix Paeoniae Rubra on the resistance gene of Staphylococcus aureus.

2021-01-30 | GSE165791 | GEO

Genome-wide analysis of global and caste-specific DNA methylation in two ant species: Camponotus floridanus and Harpegnathos saltator

Project description:This SuperSeries is composed of the following subset Series: GSE31344: smRNA sequencing of queen and virgin queen of two ants: Camponotus floridanus and Harpegnathos saltator GSE31346: Transcriptome sequencing of queen and virgin queen of two ants: Camponotus floridanus and Harpegnathos saltator GSE31576: Single base resolution methylome of two ants: Camponotus floridanus and Harpegnathos saltator Refer to individual Series

2012-08-08 | E-GEOD-31577 | biostudies-arrayexpress

A chromatin link to caste identity in the carpenter ant Camponotus floridanus

Project description:The goal of this study was to assay the extent of variation in chromatin organization between 3 ant castes (major and minor female workers and males) in one colony of Camponotus floridanus carpenter ant using ChIPseq. 45 samples total: 30 ChIP samples and 3 inputs for total histone H3, 7 histone H3 PTMs and RNA Pol II in major, minor, and male ants; CBP in major and minor ants; the major H3K27ac sample was replicated. 4 ChIP samples for H3 and H3K27ac in brains of majors and minors, and 2 inputs. 2 RNAseq samples for major and minor ants head+thorax; 4 RNAseq samples for brain (majors and minors with 2 replicates each).

2012-11-26 | E-GEOD-37523 | biostudies-arrayexpress

Project description:Microbial Diversity of Central European Forests

| PRJNA932736 | ENA

Project description:Comana monomorpha venomics

| PRJNA1086036 | ENA

Acharia stimulea

Project description:Acharia stimulea venomics

| PRJNA932547 | ENA

Project description:Do morphologically distinct groups correspond to reproductively isolated species? A case study in Myrmica ants from Switzerland

| PRJNA1188312 | ENA

Small RNA sequencing and analysis of two ants: Camponotus floridanus and Harpegnathos saltator

Project description:Deep sequencing of small RNA from two Ants: Camponotus floridanus and Harpegnathos saltator

2010-08-27 | GSE22679 | GEO