Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Study of the virome of Dothistroma septosporum

PROVIDER: PRJNA813395 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18252048_1.fastq.gz	Fastqsanger.gz
	SRR18252048_2.fastq.gz	Fastqsanger.gz
	SRR18252049_1.fastq.gz	Fastqsanger.gz
	SRR18252049_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Project description:Dothistroma septosporum comparative genomics

| PRJNA381823 | ENA

Project description:Dothistroma septosporum Laea knock out

| PRJNA422893 | ENA

Project description:Dothistroma septosporum population New Zealand

| PRJNA426106 | ENA

Dothistroma septosporum population study

Project description:Population genomic study of Dothistroma septosporum in the UK

| PRJEB14366 | ENA

Dothistroma septosporum NZE10

Project description:Dothistroma septosporum NZE10 EST - Dotse_DsPine transcriptome

| PRJNA584643 | ENA

Dothistroma septosporum NZE10

Project description:Dothistroma septosporum NZE10 EST - Dotse_DsRich transcriptome

| PRJNA584708 | ENA

undefined

Project description:Sequencing of Dothistroma septosporum chrysovirus-1

| PRJEB57200 | ENA

Dothistroma septosporum NZE10

Project description:Dothistroma septosporum NZE10 Genome sequencing and assembly

| PRJNA74753 | ENA

The unexpected role of HBx in UC

Project description:Ulcerative colitis is a chronic inflammatory disorder for which a definitive cure is still missing. This is characterized by an overwhelming inflammatory milieu in the colonic tract where a composite set of immune and non-immune cells orchestrate its pathogenesis. Over the last years, a growing body of evidence has been pinpointing gut virome dysbiosis as underlying its progression. Nonetheless, its role during the early phases of chronic inflammation is far from being fully defined. Here we show the gut virome-associated Hepatitis B virus protein X, most likely acquired after an event of zoonotic spillover, to be associated with the early stages of ulcerative colitis and to induce colonic inflammation in mice. It acts as a transcriptional regulator in epithelial cells, provoking barrier leakage and altering mucosal immunity at the level of both innate and adaptive immunity. This study paves the way to the comprehension of the aetiopathogenesis of intestinal inflammation and encourages further investigations of the virome as a trigger also in other scenarios. Moreover, it provides a brand-new standpoint that looks at the virome as a target for tailored treatments, blocking the early phases of chronic inflammation and possibly leading to better disease management.

2023-02-20 | GSE204665 | GEO

Project description:Apple virome study

| PRJNA1115969 | ENA