Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Mouse intestinal microorganism with CA

PROVIDER: PRJNA813996 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR18273874_1.fastq.gz	Fastqsanger.gz
	SRR18273874_2.fastq.gz	Fastqsanger.gz
	SRR18273875_1.fastq.gz	Fastqsanger.gz
	SRR18273875_2.fastq.gz	Fastqsanger.gz
	SRR18273876_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 30

Similar Datasets

Project description:Mouse intestinal microorganism

| PRJNA726844 | ENA

Project description:Mouse intestinal microorganism for FMT

| PRJNA726847 | ENA

Intestinal microecology of lung cancer patients with brain metastasis

Project description:Interventions: Case series:N/A Primary outcome(s): Serum immune cytokines;Blood immune cells;SCFAs of bacterial metabolites;Gut microbial genomics;Metabolic function of intestinal microorganism Study Design: Sequential

| 2706719 | ecrin-mdr-crc

Project description:Bats intestinal microorganism

| PRJNA741584 | ENA

Project description:Takin intestinal microorganism

| PRJNA942578 | ENA

Protein Kinase A (PKAc alpha ) regulates gastric homeostasis and preneoplastic lesions

Project description:We generated a novel Six2-Cre+/-PKAcaRfl/wt (CA-PKA) CA-PKA mouse in which expression of constitutive-active PKAcaR was induced in gastric mesenchyme progenitors. CA-PKA mice showed disruption of gastric homeostasis characterized by aberrant mucosal development and epithelial hyperproliferation; ultimately developing multiple features of gastric corpus preneoplasia including decreased parietal cells, mucous cell hyperplasia, spasmolytic peptide expressing metaplasia (SPEM) with intestinal characteristics and dysplastic and invasive cystic glands. Our results show that constitutively active PKAcaR in the stomach mesenchyme nonautonomously disrupts gastric homeostasis characterized by increased epithelial proliferation and aberrant epithelial maldevelopment, ultimately leading to gastric preneoplasia.

2022-09-20 | GSE196236 | GEO

Candidates for bile acid-dependent PPARα-target genes in mouse intestinal cells

Project description:In addition to their role as a digestive detergent, bile acids have the ability to modulate the expression of genes. The intestinal content of cholic acids (CA) fluctuated in response to the daily feeding-fasting cycle; therefore, we hypothesized that the temporal accumulation of CA may affect the expression of genes in intestinal epithelial cells. To screen bile acid-regulated genes, we performed oligonucleotide microarray analyses using RNA isolated from the CA-treated intestinal cells of mice. Several types of genes were screened as candidates for bile acid-regulated genes. They included genes that encoded lipid metabolism-related proteins, receptors, transcriptional factors, and plasma-membrane transporters.

2015-08-01 | GSE55443 | GEO

Vitamin D Receptor binding and chromatin accessibility in mouse duodenal crypt and villus and colon epithelium

Project description:VDR is critical for Ca++ homeostasis. While its role in this process within the intestine has primarily been focused to the duodenal epithelium, we have uncovered a compensatory role for VDR in the colon in mediating Ca++ uptake. Here, we compare VDR genomic binding properties in the colon and duodenum using ChIP-seq. We also examine the chromatin accessibility between these intestinal regions.

2023-11-06 | GSE161038 | GEO

Project description:Intestinal microorganism of silkworm

| PRJNA796270 | ENA

Project description:Hybrid sturgeon Intestinal microorganism

| PRJNA1020435 | ENA