Project description:Early diagnosis of cancer has been shown to substantially improve 5-year survival rates for many cancer types. With current methodologies early diagnosis has proven difficult for cancers of deep tissues, such as the pancreas and lung. However, whole peripheral blood has been demonstrated to be a promising non-invasive surrogate tissue for the detection of many types of cancer. Blood samples were collected in EDTA blood collection tubes from 2,485 human volunteers and gene expression profiled with the goal to develop a classification model that differentiations patients with cancer from those without cancer.

2024-08-31 | GSE203024 | GEO

Expression data from umbilical cord blood and peripheral blood stem cell-derived monocytes of human

Project description:Expression data from umbilical cord blood and peripheral blood stem cell-derived monocytes of human

| PRJNA528106 | ENA

Characterization of Data Variation in Gene Expression Profiling of Human Peripheral Blood Samples

Project description:We conducted a study on variation in the human peripheral blood transcriptome using the PAXgeneTM Blood RNA System (PreAnalytix) and GeneChip Human Genome U133 plus 2.0 Array (Affymetrix). Data regarding the RNA integrity number (RIN) and complete blood count (CBC) for each healthy individual were collected and combined with gene expression profiles to characterize both biological and technological variation. The effect of RNA sample degradation on microarray performance in peripheral blood transcriptome analysis was also investigated.

2011-01-01 | E-MEXP-2917 | biostudies-arrayexpress

Expression data from Rapamycin treated Peripheral blood derived macrophages

Project description:Expression data from Rapamycin treated Peripheral blood derived macrophages

| PRJNA510583 | ENA

Expression data from umbilical cord blood and peripheral blood stem cell-derived monocytes of human

Project description:To identify the differences between human umbilical cord blood and peripheral blood monocytes, we performed unsupervised bioinformatic analyses by microarrays.

2021-05-18 | GSE128562 | GEO

Expression data for peripheral human blood leukocytes gene expression

Project description:Gene expression level in PBLs (peripheral blood leukocytes) could serve as biomarkers for symptomatic knee osteroarthritis (OA). We used microarrays to detail the significant genes that are down/up regulated in OA PBLs by studying both the control and OA groups. We would like to acknowledge NIAMS support through (AR052873 & AR054817) and U01-AR050911.

2017-01-01 | GSE63359 | GEO

Expression data from peripheral blood

Project description:C1q expression increases significantly in the peripheral blood of patients with active tuberculosis compared to healthy controls and individuals with latent TB infection. The percentage of C1q-expressing CD14 positive cells is significantly increased in active TB patients. C1q expression in the peripheral blood correlates with sputum smear positivity in tuberculosis patients and is reduced after anti-tuberculosis chemotherapy. Notably, receiver operating characteristic analysis showed that C1qC mRNA levels in peripheral blood efficiently discriminate active from latent tuberculosis infection and healthy controls. Additionally, C1qC protein level in pleural effusion shows improved power in discriminating tuberculosis from non-tuberculosis pleurisy when compared to other inflammatory markers, such as IL-6 and TNF-α C1q expression correlates with active disease in human tuberculosis. C1q could be a potential diagnostic marker to discriminate active tuberculosis from latent tuberculosis infection as well as tuberculosis pleurisy from non-tuberculosis pleurisy.

2014-02-15 | GSE54992 | GEO

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