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Gene expression profile at single cell level of islet cells from CD and HFD mice

ABSTRACT: Gene expression profile at single cell level of islet cells from CD and HFD mice

PROVIDER: PRJNA839708 | ENA |

REPOSITORIES: ENA

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Gene expression profile at single cell level of islet cells from CD and HFD mice

Project description:High-throughput scRNA-seq transcriptionally profiled an estimated 15093 cells from CD islets and 18906 from HFD islets. The mean number of reads per sequenced cell was 43,301 for CD islets and 33,867 for HFD islets, while the median number of genes per sequenced cell was 2105 and 1775, respectively.

2022-11-30 | GSE203376 | GEO

RNAseq of mRNA from splenic and hepatic CD8 T cells in ND and CD-HFD mice

Project description:In this study we want to compare the gene expression profile of CD44+CXCR6+ CD8+ T cells from the liver of ND and CD-HFD mice with hepatic CD44+CXCR6neg and splenic CD44+ CX3CR1neg CD8 T cells of ND and CD-HFD mice. This comparison will reveal transcriptional signatures of hepatic CD44+CXCR6+ CD8+ T cells in CD-HFD responsible for causing liver pathology in NASH.

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Gene expression profile at single cell level of mouse heart from control diet (CD), high fat diet (HFD) and Western diet (WD)

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Analysis of genomic aberrations by array comparative genomic hybridization (aCGH) of tumor tissues of mice after 12 months on CD-HFD (n= 9) or 12 months on CD-HFD plus 8 weeks treatment with α-PD-1 (n= 12)

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Transcriptome analysis reveals key genes and pathways that macrophage of islet in NCD(normal chow feed) or HFD( high fat feed)

Project description:Our research is helpful to understand the physiological and pathological level changes caused on the macrophages of islet in HFD conditional, to find the different mechanism or signaling pathway compared with NCD

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Gene expression profile at single cell level of mouse heart from control diet (CD), high fat diet (HFD) and Western diet (WD)

Project description:Gene expression profile at single cell level of mouse heart from control diet (CD), high fat diet (HFD) and Western diet (WD)

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Project description:We perform scRNA-seq in the livers of C57BL/6 mice fed a CD-HFD or control diet for 3 months (NAFLD), 6 months (NASH) or 15 months (HCC)

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miRNA sequencing of islet-drived exosomes in HFD mice

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