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Whole-transcriptome sequencing and ceRNA interaction network construction for temporomandibular joint osteoarthritis [RNA-Seq]

ABSTRACT: Whole-transcriptome sequencing and ceRNA interaction network construction for temporomandibular joint osteoarthritis [RNA-Seq]

PROVIDER: PRJNA855869 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR19977569_1.fastq.gz	Fastqsanger.gz
	SRR19977569_2.fastq.gz	Fastqsanger.gz
	SRR19977570_1.fastq.gz	Fastqsanger.gz
	SRR19977570_2.fastq.gz	Fastqsanger.gz
	SRR19977571_1.fastq.gz	Fastqsanger.gz

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Project description:Temporomandibular joint osteoarthritis (TMJ-OA), a subtype of temporomandibular joint dysfunction (TMD), is characterized by progressive cartilage degradation, subchondral bone erosion, and chronic pain. Although there has been extensive research on TMJ-OA, its etiology remains unknown. Age, hormonal factors, and excessive mechanical stress on the TMJ are proposed risk factors for TMJ-OA. Using microarrays, we discovered two disease susceptibility genes that have been suggested to be involved in the pathogenic mechanism of TMJ-OA.

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