Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series3 - Chromatin profiles, ChIP-seq)

ABSTRACT: Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series3 - Chromatin profiles, ChIP-seq)

PROVIDER: PRJNA857288 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR20068204_1.fastq.gz	Fastqsanger.gz
	SRR20068204_2.fastq.gz	Fastqsanger.gz
	SRR20068205_1.fastq.gz	Fastqsanger.gz
	SRR20068205_2.fastq.gz	Fastqsanger.gz
	SRR20068206_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 80

Similar Datasets

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells

Project description:Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells

| PRJNA857289 | ENA

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series1 - Transcriptome)

Project description:Using a unique model of cultured human beta cell senescence we show that chromatin reorganization leads to activation of enhancers regulating functional maturation genes, concomitantly with acquisition of glucose-stimulated insulin secretion capacity. Interferon-response genes are elevated in senescent beta cells, but cytokine-encoding senescence-associated secretory phenotype (SASP) genes are not. Human beta cell senescence thus involves chromatin-driven upregulation of a functional maturation program and of interferon-stimulated genes, changes that could increase both insulin secretion and immune reactivity.

2024-06-26 | GSE207816 | GEO

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series2 - chromatin sccessibility, ATAC-seq)

2024-06-26 | GSE207818 | GEO

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series4- chromatin profiles, MINT-ChIP)

2024-06-26 | GSE207825 | GEO

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series3 - Chromatin profiles, ChIP-seq)

2024-06-26 | GSE207822 | GEO

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series1 - Transcriptome)

Project description:Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series1 - Transcriptome)

| PRJNA857278 | ENA

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series2 - chromatin sccessibility, ATAC-seq)

Project description:Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series2 - chromatin sccessibility, ATAC-seq)

| PRJNA857284 | ENA

Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series4- chromatin profiles, MINT-ChIP)

Project description:Chromatin reorganization drives expression of functional maturation genes in senescent pancreatic beta cells (Series4- chromatin profiles, MINT-ChIP)

| PRJNA857292 | ENA

Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identity

Project description:Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identity

| PRJNA770644 | ENA

Transcriptome reorganization during wood maturation in Pinus radiata

Project description:Wood maturation produces two distinct wood tissues: juvenile wood (JW) and mature wood (LW), which are the major cause of wood qaulity variation within a tree. We investigate transcriptome reorganization during wood maturation process in radiata pine using a newly developed 18k cDNA microarrays.

2011-06-01 | GSE20535 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data