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The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity [CUT&TAG]

ABSTRACT: The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity [CUT&TAG]

PROVIDER: PRJNA858782 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR20207373_1.fastq.gz	Fastqsanger.gz
	SRR20207373_2.fastq.gz	Fastqsanger.gz
	SRR20207374_1.fastq.gz	Fastqsanger.gz
	SRR20207374_2.fastq.gz	Fastqsanger.gz
	SRR20207375_1.fastq.gz	Fastqsanger.gz

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Expression comparison between SMC4 and conventional cultures

Project description:The undifferentiated state of pluripotent stem cells depends heavily on the culture conditions. We show that a unique combination of small molecules, SMC4, added to culture conditions converts primed pluripotent stem cells to a more naïve state. By conducting Affymetix analysis we show of majority of lineage markers are repressed in SMC4 culture.

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