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Analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

ABSTRACT: Analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

PROVIDER: PRJNA867585 | ENA |

REPOSITORIES: ENA

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Gene expression analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

Project description:We performed gene expression profiling analysis using data obtained from RNA-seq of a paraganglioma sample carrying the DLST-p.Y422C mutation. The main goal of this project was to find specific gene expression profiles associated to the presence of mutations in the DLST gene of pheochromocytomas/paragangliomas.

2023-05-05 | GSE210808 | GEO

Epigenome analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation [methylation array]

Project description:Genome wide DNA methylation profiling of a paraganglioma sample carrying the DLST-p.Y422C mutation. The Illumina Infinium EPIC Human DNA methylation Beadchip v1.2 was used to obtain a DNA methylation profile across approximately 850,000 CpGs. The main goal of this project was to find specific methylation profiles associated to the presence of mutations in the DLST gene of pheochromocytomas/paragangliomas.

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Gene expression analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

Project description:Gene expression analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

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Project description:Epigenome analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation [methylation array]

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Epigenome analysis of a pheochromocytoma sample carrying co-ocurrent mutations in NF1 and DLST.

Project description:Genome wide DNA methylation profiling of a pheochromocytoma sample carrying co-ocurrent mutations in NF1 and DLST. The Illumina Infinium EPIC Human DNA methylation Beadchip v1.2 was used to obtain a DNA methylation profile across approximately 850,000 CpGs. The main goal of this project was to gain insight into the role of these events in tumour development.

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Analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

Project description:This SuperSeries is composed of the SubSeries listed below.

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Epigenome analysis of a pheochromocytoma sample carrying co-ocurrent mutations in NF1 and DLST.

Project description:Epigenome analysis of a pheochromocytoma sample carrying co-ocurrent mutations in NF1 and DLST.

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Gene expression analysis of pheochromocytoma samples carrying co-occurrent mutations in NF1 and DLST.

Project description:We performed gene expression profiling analysis using data obtained from RNA-seq of two pheochromocytoma samples carrying co-occurrent mutations in NF1 and DLST. The main goal of this project was to to gain insight into the role of these events in tumour development.

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DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation and metabolic remodeling

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