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Gene expression analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

ABSTRACT: Gene expression analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

PROVIDER: PRJNA867591 | ENA |

REPOSITORIES: ENA

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Gene expression analysis of a paraganglioma sample carrying the DLST-p.Y422C mutation

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Project description:This SuperSeries is composed of the SubSeries listed below.

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Project description:We performed gene expression profiling analysis using data obtained from RNA-seq of two pheochromocytoma samples carrying co-occurrent mutations in NF1 and DLST. The main goal of this project was to to gain insight into the role of these events in tumour development.

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DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation and metabolic remodeling

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