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The binding pattern of HOXA5 in the genome of extrahepatic cholangiocarcinoma cells

ABSTRACT: The binding pattern of HOXA5 in the genome of extrahepatic cholangiocarcinoma cells

PROVIDER: PRJNA873710 | ENA |

REPOSITORIES: ENA

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The binding pattern of HOXA5 in the genome of extrahepatic cholangiocarcinoma cells

Project description:HOXA5 is a transcription factor in mammalian and can regulate cell differentiation, proliferation and apoptosis as well as tumorigenesis. However, little is known on whether and how HOXA5 can regulate the malignant behaviors of cholangiocarcinoma. The binding pattern of HOXA5 was evaluated by CUT & Tag assay. The differential peaks were analysed to assess the role of HOXA5 in the regulation of the key genes involved in cell proliferation and DNA replication.

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The role HOXA5 in extrahepatic cholangiocarcinoma (Methylation)

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Project description:The overall objective of this study was to explore aberrantly expressed microRNAs (miRNAs) and investigate their clinical significances in patients with extrahepatic cholangiocarcinoma (ECCA).

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Project description:This SuperSeries is composed of the SubSeries listed below.

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