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Effect of knockout of SOX9 on gene expression profile in Huh7 cells

ABSTRACT: Effect of knockout of SOX9 on gene expression profile in Huh7 cells

PROVIDER: PRJNA885012 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR21736630.fastq.gz	Fastqsanger.gz
	SRR21736631.fastq.gz	Fastqsanger.gz
	SRR21736632.fastq.gz	Fastqsanger.gz
	SRR21736633.fastq.gz	Fastqsanger.gz
	SRR21736634.fastq.gz	Fastqsanger.gz

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Effect of knockout of SOX9 on gene expression profile in Huh7 cells

Project description:To investigate the effect of SOX9 on the expression profile of Huh-7 cells, we established SOX9 knockout (SOX9KO)Huh-7 cells by crisper-cas9 system.We then performed gene expression profiling analysis using data obtained from RNA-seq of Huh-7 and SOX9KO Huh-7 cells.

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Project description:We compared gene expression profile of jejunum crypt samples of Sox9 deficient mice and wild type control mice in order to identify the genes that are regulated by SOX9 in the small intestinal crypt epithelial cells. The intestinal epithelial cells were collected from crypts of jejunum of three 3-mo-old Sox9 mutant mice and three littermate controls.

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