Ontology highlight
ABSTRACT:
PROVIDER: PRJNA885499 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR22281914_1.fastq.gz | Fastqsanger.gz | |||
| SRR22281914_2.fastq.gz | Fastqsanger.gz | |||
| SRR22281915_1.fastq.gz | Fastqsanger.gz | |||
| SRR22281915_2.fastq.gz | Fastqsanger.gz | |||
| SRR22281916_1.fastq.gz | Fastqsanger.gz |
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Project description:we report a transcriptome-wide comparative investigation between surface and cave species in Sinocyclocheilus. De novo transcriptome assemblies were performed on surface and cave species; then the Sinocyclocheilus contigs were annotated with Gene Ontology. RNA-Seq assays revealed reduced transcription of a series of visual phototransduction and retinal disease related genes in cave-dwelling species compared with surface species. Degeneration of the retina in Sinocyclocheilus cavefish might occur in a lens-independent way by the down-regulation of several transcriptional factors, which have direct roles in retina development and maintenance, such as crx, rorb and Wnt pathway members.
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