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ABSTRACT: Draft Genome Sequence of Vibrio harveyi 22FBVib0145 isolated from Olive flounder (Paralichthys olivaceus)

PROVIDER: PRJNA889991 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR21885128_1.fastq.gz	Fastqsanger.gz
	SRR21885129_1.fastq.gz	Fastqsanger.gz
	SRR21885129_2.fastq.gz	Fastqsanger.gz

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The time-dependent global micro-transcriptome of Japanese flounder in response to Vibrio anguillarum infection

Project description:Japanese flounder (Paralichthys olivaceus) is an economic important aquaculture fish that was susceptible to Vibrio anguillarum. To fully deciphered the molecular mechanisms underlying flounder host defense against V. anguillarum infection, we perform the micro-transcriptome analysis of founder spleen with and without V. anguillarum infection at 3 time points.

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Project description:Gene expression profiles by microarray have contributed for a elucidation of an immune-response and a determination of efficiency in vaccination. Recent day, edwardsielosis have caused a fatal damage in the aquaculture of Japanese flounder, Paralichthys olivaceus. However the formalin killed-cell vaccines made from Edwardsiella tarda isolated same fish species were not efficient. Recent our study revealed the mixed FKC vaccine made from the two different type of E. tarda protected Japanese flounder against Edwardsiella tarda infection for long-term. In this study, we analyzed the immune-response of a vaccinated fish kidney using the mixed FKC vaccine against Edwardsiella tarda with an Agilent custom-oligo DNA microarray on 9,573 probes of Japanese flounder. Our study revealed that the mixed FKC vaccine confered a strong immune-response and keeped a efficient for long-term on Japanese flounder.

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