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Effect of PT2385 treatment during cytotrophoblast differentiation under hypoxia

ABSTRACT: Effect of PT2385 treatment during cytotrophoblast differentiation under hypoxia

PROVIDER: PRJNA895418 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR22084115_1.fastq.gz	Fastqsanger.gz
	SRR22084115_2.fastq.gz	Fastqsanger.gz
	SRR22084116_1.fastq.gz	Fastqsanger.gz
	SRR22084116_2.fastq.gz	Fastqsanger.gz
	SRR22084117_1.fastq.gz	Fastqsanger.gz

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Effect of PT2385 treatment during cytotrophoblast differentiation under hypoxia

Project description:To investigate the therapeutic effect of HIF-2 inhibitor in placental dysfunction, we used primary cytotrophoblasts isolated from human placentas at term and cultured them under 2.5% O2 for 4 days. We either treated the cells with PT2385 at 10 µmol/L or vehicle and then performed gene expression profiling analysis using data obtained from RNA-seq of 3 different placentas.

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