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Maladaptive upregulation of aminoprocalcitonin fuels seizure self-sustaining by boosting energy supply in refractory status epilepticus

ABSTRACT: Maladaptive upregulation of aminoprocalcitonin fuels seizure self-sustaining by boosting energy supply in refractory status epilepticus

PROVIDER: PRJNA901466 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR22282110_1.fastq.gz	Fastqsanger.gz
	SRR22282110_2.fastq.gz	Fastqsanger.gz
	SRR22282111_1.fastq.gz	Fastqsanger.gz
	SRR22282111_2.fastq.gz	Fastqsanger.gz
	SRR22282112_1.fastq.gz	Fastqsanger.gz

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Maladaptive upregulation of aminoprocalcitonin fuels seizure self-sustaining by boosting energy supply in refractory status epilepticus

Project description:To investigate the biological functions of aminoprocalcitonin (NPCT) and its parent peptide procalcitonin (PCT) in neurons, we stimulated rat primary hippocampal neurons at DIV7 with 1 nM NPCT and 1 nM PCT for 24 h, respectively. Alterations in transcriptomes were analyzed with RNA-seq.

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microRNAs profiling in hippocampal cells of Self-Sustaining Status Epilepticus (SSSE) mouse model

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