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MiRNA transcription profiling in Status Epilepticus Induced Epileptogenic Process

ABSTRACT: miRNA array comparing the transcription profile of control rats and rats after intra-hippocampal pilocarpine-induced Status Epilepticus (PILO-SE).

ORGANISM(S): Rattus norvegicus

SUBMITTER: Daniel Gitai

PROVIDER: E-MTAB-4633 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Identification of microRNAs with Dysregulated Expression in Status Epilepticus Induced Epileptogenesis.

Araújo Mykaella Andrade de MA Marques Thalita Ewellyn Batista Sales TE Octacílio-Silva Shirley S Arroxelas-Silva Carmem Lúcia de CL Pereira Marília Gabriella Alves Goulart MG Peixoto-Santos José Eduardo JE Kandratavicius Ludmyla L Leite João Pereira JP Garcia-Cairasco Norberto N Castro Olagide Wagner OW Duzzioni Marcelo M Passos Geraldo Aleixo GA Paçó-Larson Maria Luisa ML Góes Gitaí Daniel Leite DL

PloS one 20161003 10

The involvement of miRNA in mesial temporal lobe epilepsy (MTLE) pathogenesis has increasingly become a focus of epigenetic studies. Despite advances, the number of known miRNAs with a consistent expression response during epileptogenesis is still small. Addressing this situation requires additional miRNA profiling studies coupled to detailed individual expression analyses. Here, we perform a miRNA microarray analysis of the hippocampus of Wistar rats 24 hours after intra-hippocampal pilocarpine ...[more]

PMID: 27695061

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