Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA sequencing of TCF19 knockdown by siRNA in endometrial cancer cells

ABSTRACT: RNA sequencing of TCF19 knockdown by siRNA in endometrial cancer cells

PROVIDER: PRJNA902340 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22311785_1.fastq.gz	Fastqsanger.gz
	SRR22311785_2.fastq.gz	Fastqsanger.gz
	SRR22311786_1.fastq.gz	Fastqsanger.gz
	SRR22311786_2.fastq.gz	Fastqsanger.gz
	SRR22311787_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

RNA sequencing of TCF19 knockdown by siRNA in endometrial cancer cells

Project description:In our study, TCF19 was found to be upregulated in microsatellite instability (MSI) endometrial cancer and was associated with poor prognosis and immune exhaustion signature. Elevated TCF19 enhanced cell proliferation and migration, which promoted tumorigenicity under non-immunological background; Moreover, tumoral TCF19 expression could also promote CD8+T cell exhaustion in tumor immune microenvironment, which facilitated immune escape and tumor development. Therefore, TCF19 could be a promising biomarker and effective therapeutic target for MSI endometrial cancer.

2023-08-11 | GSE218098 | GEO

Chromatin Immunoprecipitation(ChIP)-seq of TCF19 in endometrial cancer cells

2023-08-11 | GSE218096 | GEO

Role of TCF19 in endometrial cancer

Project description:Role of TCF19 in endometrial cancer

| PRJNA902322 | ENA

Chromatin Immunoprecipitation(ChIP)-seq of TCF19 in endometrial cancer cells

Project description:Chromatin Immunoprecipitation(ChIP)-seq of TCF19 in endometrial cancer cells

| PRJNA902338 | ENA

Gene expression data from human endometrial cancer cells treated with siRNA targeting Efp

Project description:To examine the role of Efp in endometrial cancer cells, Ishikawa and HEC-1A cells were treated with siRNA targeting Efp (siEfp) or control siRNA (siControl). Microarray analysis showed that Efp knockdown represses NF-κB-signaling pathway-associated genes.

2018-11-20 | GSE118228 | GEO

siRNA-mediated knockdown

Project description:siRNA-mediated knockdown

| PRJNA541912 | ENA

Gene expression data from endometrial cancer patient-derived cells (EDC-PDCs) treated with Efp siRNA

Project description:To examine the role of Efp in endometrial cancer, patient-derived cells were treated with siRNA targeting Efp (siEfp) or control siRNA (siControl). siRNA-mediated Efp silencing resulted in suppressed spheroid proliferation and altered gene expression profile, featuring downregulation of genes related to cell cycle and inflammation/immune responses. This study provides an insight into alternative endometrial cancer therapeutic strategies targeting Efp.

2024-01-13 | GSE164724 | GEO

Knockdown of mineralocorticoid receptor or glucocorticoid receptor on human endometrial stromal cells and decidualization

Project description:To clarify mineralcorticoid receptor and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells. Genome-wide microarray analysis was performed on primary cultures established from 4 different patients. Stromal cell cultures were subjected to either GR or MR siRNA knockdown or control non-targeting siRNA then decidualized for four days before harvesting and RNA extraction for microarray analysis.

2012-11-28 | E-GEOD-42538 | biostudies-arrayexpress

Gene expression changes in primary human endometrial stromal cells following METTL3 knockdown during in vitro decidualization

Project description:We developed an in vitro model in which primary human endometrial stromal cells (HESCs) were induced to differentiate through treatment with MPA and 8-Br-cAMP. SiRNA-mediated knockdown of METTL3 was performed on HESCs, 6 h prior to treatment of 8-Br-cAMP and MPA.

2024-04-14 | GSE263330 | GEO

RNA sequencing of MEX3A knockdown by siRNA in ovarian cancer cells

Project description:RNA sequencing of MEX3A knockdown by siRNA in ovarian cancer cells

| PRJNA782974 | ENA