Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Identifying NFIB target genes in mammalian cells

ABSTRACT: Identifying NFIB target genes in mammalian cells

PROVIDER: PRJNA907825 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Identifying NFIB target genes in mammalian cells

Project description:NFIB is a transcription factor that can both positively and negatively regulate gene transcription. We have identified NFIB as an arginine methylation substrate of CARM1. To elucidate how CARM1 could regulate NFIB target genes by methylating NFIB, we performed this ChIP-seq to firstly identify NFIB direct binding gengs.

2022-12-15 | GSE219265 | GEO

Identifying target genes which are heterogeneously expressed

Project description:Identifying target genes which are heterogeneously expressed

| PRJNA593222 | ENA

Identifying the target genes of the arginine transcription factor ArgR

Project description:Identifying the target genes of the arginine transcription factor ArgR

| PRJNA1160839 | ENA

Identifying target genes for the long noncoding RNA, GATA2-AS1

Project description:Identifying target genes for the long noncoding RNA, GATA2-AS1

| PRJNA810047 | ENA

The NFIB/CARM1 Partnership is a Therapeutic Target for Small Cell Lung Cancer

Project description:This project identified NFI family members as CARM1 substrates. NFIB was previously reported to play a critical role in the development of small cell lung cancer. We provided evidence that the arginine methylation of NFIB is required for its oncogenic function in small cell lung cancer.

2023-02-07 | PXD038237 | Pride

NFIB: A Governor of Epithelial-Melanocyte Stem Cell Behaviour in a Shared Niche

Project description:To identify direct NFIB target genes in HFSCs, we performed chromatin immunoprecipitation and deep sequencing (ChIP-seq) analysis using FACS-isolated HFSCs. Two independent NFIB ChIP-seq experiments were conducted.

2013-02-07 | E-GEOD-42900 | biostudies-arrayexpress

Spatiotemporal regulation of GLI target genes in the mammalian limb bud

Project description:Spatiotemporal regulation of GLI target genes in the mammalian limb bud

| PRJNA253126 | ENA

Mammalian target chromosome sequencing

Project description:Mammalian target chromosome sequencing Raw sequence reads

| PRJNA285957 | ENA

The NFIB/CARM1 Axis is a Therapeutic Target for Small Cell Lung Cancer

Project description:We identified NFIB as a CARM1 substrate and showed that this transcription factor utilizes CARM1 as a coactivator. Importantly, NFIB harbors both oncogenic and metastatic activities, and is often overexpressed in small cell lung cancer (SCLC). Using a SCLC mouse model, we show that both CARM1 and the CARM1 methylation site on NFIB are critical for the rapid onset of SCLC. By performing the high-throughput sequecing analysis, we found that CARM1-null and NFIB-R388K mutant mouse SCLC tumors share the ability to regulate chromatin accessbility and have similar gene expression pattern.

2022-02-07 | GSE195843 | GEO

NFIB: A Governor of Epithelial-Melanocyte Stem Cell Behaviour in a Shared Niche

Project description:To identify direct NFIB target genes in HFSCs, we performed chromatin immunoprecipitation and deep sequencing (ChIP-seq) analysis using FACS-isolated HFSCs.

2013-02-07 | GSE42900 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data