Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Colonic mucosa of ulcerative colitis patients treated with biological agents

ABSTRACT: Colonic mucosa of ulcerative colitis patients treated with biological agents

PROVIDER: PRJNA911615 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22704900_1.fastq.gz	Fastqsanger.gz
	SRR22704900_2.fastq.gz	Fastqsanger.gz
	SRR22704894_1.fastq.gz	Fastqsanger.gz
	SRR22704894_2.fastq.gz	Fastqsanger.gz
	SRR22704895_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Colonic mucosa of ulcerative colitis patients treated with biological agents

Project description:Colonoscopy biopsies from patients with ulcerative colitis were collected prior to biological therapy. The sampled mucosa was the area of active lesion. Heterogenety of the samples were studied.

2022-12-17 | GSE220815 | GEO

Transcription profiling of human ulcerative colitis colonic mucosa to define an ulcerative colitis preinflammatory state

Project description:The samples are a part of a study aiming at diagnosing ulcerative colitis from genome-wide gene expression analysis of the colonic mucosa. Colonic mucosal samples were collected as endoscopic pinch biopsies from ulcerative colitis patients and from control subjects. Samples with and without macroscopic signs of inflammation were collected from the patients. Experiment Overall Design: The series contain eight UC samples with macroscopic signs of inflammation, 13 UC smaples without macroscopic signs of inflammation, five control subjects.

2008-06-20 | E-GEOD-9452 | biostudies-arrayexpress

Definition of an ulcerative colitis preinflammatory state

2007-10-31 | GSE9452 | GEO

Label-free quantitative proteomics of ulcerative colitis patients

Project description:Label-free quantitative proteomics for inflamed and matched normal colonic mucosa in ulcerative colitis (UC) patients was used for discovery of differential expressed proteins. Compared to normal colonic mucosa, we found that 47 upregulated proteins and 78 downregulated proteins in UC patients according to fold change ≥ 2, p ≤ 0.05. Then, we will study the potential mechanism according to differential expressed proteins

2023-04-15 | PXD041569 |

Human colon biopsies (healthy and Ulcerative Colitis) LC-MS/MS

Project description:The etiology of the inflammatory bowel diseases, including ulcerative colitis, remains incomplete, but recent findings points to the involvement of complex host-microbial interactions. We hypothesized that an analysis of the proteins on the host-microbial interacting surface, the intestinal mucosa, could reveal novel insights into the diseases. Mucosal colonic biopsies were extracted by standard colonscopy from sigmoideum from 10 ulcerative colitis patients from non-inflammed tissue and 10 controls. The biopsies were immediately following extraction snap-frozen for protein analysis and the protein content of the biopsies was characterized by high-throughput quantative gel-free proteomics.

2015-05-26 | PXD001608 | Pride

miRNA data in colon mucosa samples from individuals with ulcerative colitis and normal controls

Project description:Genome wide miRNA profiling of ulcerative colitis, and normal colon mucosa samples. The GeneChip miRNA 3.0 Array was used to obtain miRNA profiles across colon mucosa samples. Samples came from 5 ulcerative colitis affected, and 5 normal individuals.

2015-01-01 | GSE43009 | GEO

Expression data in colon mucosa samples from individuals with ulcerative colitis and normal controls

Project description:Genome wide expression profiling of ulcerative colitis, and normal colon mucosa samples. The GeneChip PrimeView Human Gene Expression Array was used to obtain expresion profiles across colon mucosa samples. Samples came from 5 ulcerative colitis affected, and 5 normal individuals.

2015-01-01 | GSE42911 | GEO

miRNA data in colon mucosa samples from individuals with ulcerative colitis and normal controls

2015-01-01 | E-GEOD-43009 | biostudies-arrayexpress

Ulcerative colitis gene expressions file

Project description:Ulcerative colitis related gene expressions analysis in colonic biopsy samples from control and ulcerative colitis patients

2019-07-10 | GSE134025 | GEO

Ulcerative colitis biopsies analyzed by PCT-SWATH mass spectrometry

Project description:Ulcerative colitis (UC) is an idiopathic chronic inflammatory disorder of the colonic mucosa with rising incidence. Despite numerous known genetic risk loci environmental factors seem to be crucial in the pathogenesis of this complex disease with suboptimal treatment options. Approaches utilizing methods of systemic biology have been started to use in the analysis of mucosal biopsies in order to get a more comprehensive view of the changes related to the disorder. Our aim was to test the capability of a new mass spectrometry (MS) -based assay (PCT-SWATH mass spectrometry) to characterize host proteomes both in inflamed and non-inflamed colon tissues of an UC patient cohort.

2017-06-12 | PXD004907 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data