Effect of depletion of TFII-I or TRIM24 on Jurkat T cell activation.
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ABSTRACT:
PROVIDER: PRJNA915097 | ENA |
REPOSITORIES: ENA
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Project description:To investigate the cooperative function TFII-I and TRIM24 in the regulation of T cell activation regulated genes, we established Jurkat Tat cells in which TFII-I was depleted by shRNA and TRIM24 was knocked out by CRISPR-Cas9. We then performed gene expression profiling analysis using data obtained from RNA-seq of cell lines stimulated by PMA and Ionomycin.
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