Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome changes following acute serine starvation in breast cancer cells

ABSTRACT: Transcriptome changes following acute serine starvation in breast cancer cells

PROVIDER: PRJNA919009 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22998200_1.fastq.gz	Fastqsanger.gz
	SRR22998200_2.fastq.gz	Fastqsanger.gz
	SRR22998201_1.fastq.gz	Fastqsanger.gz
	SRR22998201_2.fastq.gz	Fastqsanger.gz
	SRR22998202_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Epigenomic changes following acute serine starvation in breast cancer cells

Project description:Epigenomic changes following acute serine starvation in breast cancer cells

| PRJNA919038 | ENA

Transcriptomic and epigenomic changes following acute serine starvation in breast cancer cells

Project description:Transcriptomic and epigenomic changes following acute serine starvation in breast cancer cells

| PRJNA919049 | ENA

Epigenomic changes following acute serine starvation in breast cancer cells

Project description:Genome wide H3K27ac CHIP sequencing was performed in the ER positive breast cancer cell line MCF7 cultured in serine-free media for 24h, with or without supplementation with 2 mM glycerol triacetate.

2023-08-01 | GSE222341 | GEO

Transcriptome changes following acute serine starvation in breast cancer cells

Project description:We cultured the ER negative breast cancer cell line MDA-MB-231 and the ER positive breast cancer cell line MCF7 in serine-free media for 24h. RNA was extracted from the cells and submitted for RNA sequencing.

2023-08-01 | GSE222313 | GEO

Transcriptomic and epigenomic changes following acute serine starvation in breast cancer cells

Project description:This SuperSeries is composed of the SubSeries listed below.

2023-08-01 | GSE222343 | GEO

RNA seq of MLL-ENL transformed cells under serine/glycine starvation including a starvation resistant clone

Project description:Primary hematopoietic cells were transformed by retrovirally transduced MLL-ENL. The resulting cell population was either cultured in full medium or under starvation conditions without serine and glycine. In addition a spontaneously arising ser/gly starvation resistant clone was included in this experiment. Nascent RNA was isolated by labeling cells for 1h with 4-thio-uridine and subsequent biotinylation of labeled RNA followed by streptavidin chromatography as described in Garcia-Cuellar et al. CellReports S22111247(16)30259-5.

2021-06-21 | E-MTAB-8738 | biostudies-arrayexpress

RNA seq of MLL-ENL transformed cells under serine/glycine starvation including a starvation resistant clone

Project description:RNA seq of MLL-ENL transformed cells under serine/glycine starvation including a starvation resistant clone

| PRJEB36459 | ENA

Dietary methionine starvation impairs acute myeloid leukemia progression

Project description:Dietary methionine starvation impairs acute myeloid leukemia progression

| PRJNA909277 | ENA

Elucidating BT4338 binding in Bacteroides thetaiotaomicron following 10 minutes of carbon starvation.

Project description:Use ChIPseq to elucidate BT4338 binding in Bacteroides thetaiotaomicron following 10 minutes of carbon starvation.

2019-12-19 | GSE134116 | GEO

Ribosome profiling and RNA-seq of an acute glucose starvation timecourse and 5 day growth course in S. cerevisiae

Project description:Ribosome profiling provides an opportunity to not only assess how the relative abundance of ribosome association with mRNAs changes in different conditions, but to look more closely at where along mRNAs those ribosomes bind. Here, we used ribosome profiling to calculate the ribosome polarity scores and changes in ribosome footprint read density in both aggregate and gene-specific ways. We profiled a time course of acute glucose starvation followed by glucose readdition and a multi-day growth course through the diauxic shift into stationary phase. We found that ribosome polarity became positive in postdiauxic shift conditions relative to log phase. In acute starvation, polarity shifted positive at our earliest time points but did not continue to do so at later time points. This is consistent with a read density analysis which demonstrated increased density on the 3’ half of genes after glucose starvation. Additionally, we performed ribosome profiling in samples that had glucose added back following acute starvation and observed a wave of new ribosome movement near the start codon and approximately 2,000 nucleotides downstream on open reading frames after one and five minutes of readdition, respectively. Our ribosome profiling analysis suggested that elongation slows during starvation which leads to a buildup of ribosomes on the 3’ halves of mRNAs. Further, it also indicated ribosomes previously built up can resume translation upon glucose readdition. We used reporter assays to corroborate these findings in vivo. Together, these results demonstrate how yeast regulate translation in response to glucose starvation.

2022-04-11 | GSE200491 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data