Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (snRNAseq)

ABSTRACT: Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (snRNAseq)

PROVIDER: PRJNA922963 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (snRNAseq)

Project description:To investigate the efect of extracellular bilirubin and intracellular ascorbate on the development of zonal hepatocytes in human liver organoids.

2024-09-18 | GSE222648 | GEO

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity

Project description:Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity

| PRJNA922964 | ENA

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (ChIPseq)

Project description:Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (ChIPseq)

| PRJNA922973 | ENA

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (RNA-seq)

Project description:Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (RNA-seq)

| PRJNA922949 | ENA

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (ChIPseq)

Project description:To investigate the efect of extracellular bilirubin and intracellular ascorbate on the development of zonal hepatocytes in human liver organoids.

2024-09-18 | GSE222653 | GEO

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (RNA-seq)

Project description:To investigate the efect of extracellular bilirubin and intracellular ascorbate on the development of zonal hepatocytes in human liver organoids

2024-09-18 | GSE222641 | GEO

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity

Project description:This SuperSeries is composed of the SubSeries listed below.

2024-09-18 | GSE222654 | GEO

Single nucleus RNAseq of mouse astrocytes after traumatic spinal cord injury

Project description:We conducted snRNAseq of mouse astrocytes after traumatic spinal cord injury (SCI). These data reveal transcriptomic similarities and differences among astrocytes in healthy spinal cord and after spinal cord injury.

2024-01-09 | GSE247844 | GEO

NFI transcription factors regulate zonal olfactory receptor expression

Project description:Expression of one out of > 1000 olfactory receptor (OR) genes is stochastic, yet organized into anatomic "zones" along the dorsoventral axis of the olfactory epithelium. Here we profile the gene expression, chromatin state and nuclear architecture of olfactory sensory neurons and olfactory progenitors of different zones. We discovered that zonal OR expression is specified by two processes: low-level polygenic transcription of OR genes in olfactory progenitors, as wells as the chromatin structure and nuclear architecture during olfactory differentiation. Specifically, in cells of any zonal segment, polygenic transcription in olfactory progenitors defines the OR repertoire eligible for OR choice as the cells mature, while an increased level of heterochromatin and chromatin compaction represses ectopic more dorsally expressed ORs. We find that this process is regulated by the NFI family of transcription factors that are expressed in a graded fashion in the olfactory epithelium. Conditional deletion of NFI A, B, and X results in a transformation of the chromatin state and nucellar architecture and an accompanying shift in the preferred OR repertoire.

2023-06-14 | GSE158730 | GEO

snRNAseq of human limbus tissue

Project description:snRNAseq of human limbus tissue

| PRJNA935339 | ENA