Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNASeq data from OMP-52M51 acute treated T-ALL PDX mice

ABSTRACT: RNASeq data from OMP-52M51 acute treated T-ALL PDX mice

PROVIDER: PRJNA933227 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR23387485_1.fastq.gz	Fastqsanger.gz
	SRR23387485_2.fastq.gz	Fastqsanger.gz
	SRR23387486_1.fastq.gz	Fastqsanger.gz
	SRR23387486_2.fastq.gz	Fastqsanger.gz
	SRR23387487_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

RNASeq data from OMP-52M51 acute treated T-ALL PDX mice

Project description:We recently demonstrated that a human Notch1-specific neutralizing antibody (OMP-52M51) was very effective in T-ALL patient derived xenografts (PDX) bearing NOTCH1/FBW7 mutations. To evaluate the transcriptomic downstream effects of anti-NOTCH1 therapy, we perform RNA-Seq analysis in leukemia cells derived from PDTALL46 PDX mice after an acute treatment with control Ab or OMP-52M51.

2023-09-13 | GSE224988 | GEO

RNAseq of Breast cancer PDX samples

Project description:RNAseq was done on Breast cancer PDX samples uisng Library protocol =llumina TruSeq Stranded Total RNA Kit with Ribo-Zero Gold , HiSeq 125 Cycle Paired-End Sequencing v4

2018-05-24 | GSE113476 | GEO

Expression data from OMP52M51 resistant or acute treated leukemic mice

Project description:We recently demonstrated that a human Notch1-specific neutralizing antibody (OMP52M51) was very effective in T-ALL patient derived xenografts (PDX) bearing NOTCH1/FBW7 mutations. However, we observed development of acquired resistance following long-term administration of the antibody and used PDX models to investigate this phenomenon. We analyzed expression profiles to identify genes and pathways modulated in mice treated until progression or acute treated with a neutralizing antibody against Notch1.

2020-05-20 | GSE123751 | GEO

RNAseq analysis of meso PDX models

Project description:RNAseq analysis of meso PDX models

| PRJEB53372 | ENA

RNAseq of Breast cancer PDX samples

Project description:RNAseq of Breast cancer PDX samples

| PRJNA451206 | ENA

RNAseq analysis of SCLC PDX models

Project description:RNAseq analysis of SCLC PDX models

| PRJEB50684 | ENA

RNAseq analysis of transcriptome changes in MM27 metastatic melanoma PDX cells upon treatment with AURKA and/or MEK inhibitors

Project description:Purpose: Study the changes in the transcriptome of metastatic melanoma PDX cells upon combination treatment with AURKA and MEK inhibitors Methods: RNAseq analysis of melanoma PDX cells treated with AURKA inhibitor Alisertib (500nM) and MEK inhibitor trametinib (100nM) for 72 h

2023-07-07 | GSE207645 | GEO

RNAseq analysis of meso PDX models

Project description:We investigated the gene expression changes in a library of meso PDX models.

2022-06-17 | E-MTAB-11783 | biostudies-arrayexpress

RNAseq analysis of SCLC PDX models

Project description:We investigated the gene expression changes in a library of small cell lung carcinoma (SCLC) patient-derived xenograft (PDX) models.

2022-02-07 | E-MTAB-11230 | biostudies-arrayexpress

RNA sequencing data from triple-negative breast cancer patient-derived xenografts (PDX)

Project description:RNAseq was performed on WHIM2 and WHIM30 PDX mammary tumors, brain metastases, and single cell suspensions over time.

2018-03-09 | GSE110626 | GEO