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Adaptive laboratory evolution with heterologous pgi

ABSTRACT: Adaptive laboratory evolution with heterologous pgi

PROVIDER: PRJNA933234 | ENA |

REPOSITORIES: ENA

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Adaptive laboratory evolution with heterologous pgi

Project description:We used RNA-seq to profile E. coli K-12 MG1655 strains subjected to adaptive laboratory evolution after knockout of endogenous glucose-6-phosphate isomerase (pgi) and subsequent expression of heterologous version of the pgi gene from Pseudomonas aeruginosa and Bacillus megaterium.

2023-02-09 | GSE224989 | GEO

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Project description:To understand the mechanism of isopropanol tolerance of Escherichia coli for improvement of isopropanol production, we performed genome re-sequencing and transcriptome analysis of isopropanol tolerant E. coli strains obtained from parallel adaptive laboratory evolution under IPA stress.

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Rewiring the metabolic network to increase docosahexaenoic acid productivity in Crypthecodinium cohnii by fermentation supernatant-based adaptive laboratory evolution

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