Project description:This study delineated how small intestinal resident microflora impact gene expression in Paneth cells. Keywords: functional genomics; transcriptional profiling
2006-06-28 | GSE5156 | GEO
Project description:Intestinal Microflora
| PRJNA1047345 | ENA
Project description:intestinal microflora
| PRJNA948564 | ENA
Project description:Effect of amylin on intestinal microflora in mice
| PRJNA694540 | ENA
Project description:Effect of TMAE on Intestinal Microflora of Broilers
Project description:Commensal microbiota contribute to gut homeostasis and influence gene expression. Intestinal organoid culture closely represent intestinal epithelium and retain intestinal stem cells and dynamic recovery capabilities as well as all major cell types of the intestinal epithelium. We established organoid culture using colon crypts isolated from germ-free (GF), and gnotobiotic mice monocolonized either with the E.coli strain O6K13 (O) or Nissle 1917 strain (N). The expression profiles of these organoids were compared to the organoid culture isolated from conventionally reared (CR) mice in order to disclose genes differentially expressed in response to the change in the intestinal microflora composition.
