Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Oasis water, sediment, and soil samples from Southern California

ABSTRACT: Oasis water, sediment, and soil samples from Southern California Targeted loci environmental

PROVIDER: PRJNA941072 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25071100_1.fastq.gz	Fastqsanger.gz
	SRR25071100_2.fastq.gz	Fastqsanger.gz
	SRR25071200_1.fastq.gz	Fastqsanger.gz
	SRR25071200_2.fastq.gz	Fastqsanger.gz
	SRR25071300_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 470

Similar Datasets

OASIS overexpression in murine podocyte cell line

Project description:Podocyte injury is involved in the onset and progression of various kidney diseases. We previously demonstrated that the transcription factor, old astrocyte specifically induced substance (OASIS) in myofibroblasts, contributes to kidney fibrosis, as a novel role of OASIS in the kidneys. Importantly, we found that OASIS is also expressed in podocytes; however, the pathophysiological significance of OASIS in podocytes remains unknown. Upon lipopolysaccharide (LPS) treatment, there is an increase in OASIS in murine podocytes. Enhanced serum creatinine levels and tubular injury, but not albuminuria and podocyte injury, are attenuated upon podocyte-restricted OASIS knockout in LPS-treated mice, as well as diabetic mice. The protective effects of podocyte-specific OASIS deficiency on tubular injury are mediated by protein kinase C iota (PRKCI/PKCι), which is negatively regulated by OASIS in podocytes. Furthermore, podocyte-restricted OASIS transgenic mice show tubular injury and tubulointerstitial fibrosis, with severe albuminuria and podocyte degeneration. Finally, there is an increase in OASIS-positive podocytes in the glomeruli of patients with minimal change nephrotic syndrome and diabetic nephropathy. Taken together, OASIS in podocytes contributes to podocyte and/or tubular injury, in part through decreased PRKCI. The induction of OASIS in podocytes is a critical event for the disturbance of kidney homeostasis.

2022-06-22 | GSE206525 | GEO

Southern California oxygen minimum zone

Project description:Southern California oxygen minimum zone Metagenome

| PRJNA1086579 | ENA

Transcription profiling of hornyhead turbot collected from polluted and clean coastal waters in southern California and zebrafish treated with estradiol and 4 nonylphenol

Project description:A custom multi-species microarray was used to study gene expression in wild hornyhead turbot (Pleuronichthys verticalis), collected from polluted and clean coastal waters in Southern California and in laboratory male zebrafish (Danio rerio) following exposure to estradiol and 4-nonylphenol. A multi-gene cross species microarray was fabricated as a diagnostic tool to screen the effects of environmental chemicals in fish, for which there is minimal genomic information. The microarray measurement of gene expression in zebrafish, which are phylogenetically distant from turbot, indicates that this multi-species microarray will be useful for measuring endocrine responses in Pleuronectiformes and other fish for which there is minimal genomic sequence information.

2009-07-17 | E-MTAB-44 | biostudies-arrayexpress

Molecular analysis of endocrine disruption in hornyhead turbot captured from wastewater treatment plant discharge locations in Southern California

Project description:Hornyhead turbot (Pleuronichthys verticalis) captured near sewage outfalls are used as sentinel fish for monitoring exposure to industrial and agricultural chemicals of ~20 million people living in coastal southern California. Although analyses of hormones in blood and organ morphology and histology in fish are useful for assessing exposure, there is a need for quantitative and sensitive molecular measurements, as many contaminants produce subtle effects. A novel multispecies microarray and qRT-PCR were used to investigate endocrine disruption in turbot captured near sewage outfalls in San Diego, Orange County and Los Angeles California. Analysis of expression of genes involved in hormone [e.g. estrogen, androgen, thyroid] responses and xenobiotic metabolism in turbot livers was correlated with phenotypic end points.

2013-12-10 | E-MEXP-3852 | biostudies-arrayexpress

oasis metagenome

Project description:Desert Oasis strain:community Targeted loci environmental

| PRJNA311559 | ENA

Comparative genomic hybridization of Vibrio cholerae from California coastal water compared to reference strain N16961

Project description:Environmental isolates of Vibrio cholerae from California coastal water compared to reference strain N16961.

2007-05-23 | E-SMDB-4063 | biostudies-arrayexpress

Microarray of RNA from calvaria in WT and OASIS-/- (KO) mice

Project description:Investigation of whole genome gene expression level changes in OASIS KO calvaria compared to wild-type calvaria. To gain further insight into the potential mechanisms underlying the defective bone formation in OASIS KO mice, we compared the gene expression in calvaria between WT and OASIS KO mice using a microarray. Each sample of total RNA was collected from a number of mice.

2010-05-05 | E-GEOD-18062 | biostudies-arrayexpress

Microarray of RNA from calvaria in WT and OASIS-/- (KO) mice

2009-09-10 | GSE18062 | GEO

Euphotic marine water from the Southern California Current System

Project description:Euphotic marine water from the Southern California Current System Raw sequence reads

| PRJNA831817 | ENA

GNPS - Environmental Metabolomics from Red Tide, Spring 2020 at Scripps Pier (San Diego, Southern California), TOM + SSA

Project description:NT LC-MS/MS based environmental metabolomics of TOM + SSA (PPL extracted) from Red Tide Spring 2020 at Scripps Pier (Southern California). Pos and Neg mode.

2020-06-05 | MSV000085555 | GNPS

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data