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The role and mechanism of R-spondin3 in pulmonary vascular barrier dysfunction induced by mechanical ventilation

ABSTRACT: The role and mechanism of R-spondin3 in pulmonary vascular barrier dysfunction induced by mechanical ventilation

PROVIDER: PRJNA941821 | ENA |

REPOSITORIES: ENA

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The role and mechanism of R-spondin3 in pulmonary vascular barrier dysfunction induced by mechanical ventilation

Project description:To investigate the effect of lowl tidal volume (LV) ventilation on the pathological development of severe lung injury, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to influence LV-induced lung injury. A mouse model of septic lung injury induced by cecal ligation and puncture was conducted, 24 h post-CLP,mice were exposed to LV (6ml/kg) for 12h

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Age Dependent Gene Expression Responses to Inhaled Lipopolysaccharide Combined with Mechanical Ventilation

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Mechanical Ventilation Augments LPS-induced Lung Injury

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