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Mus musculus strain:KrasG12D/+ Trp53R172H/+ P48-Cre

ABSTRACT: KPC mouse model on ketogenic diet or standard chow diet - Raw sequence reads

PROVIDER: PRJNA941876 | ENA |

REPOSITORIES: ENA

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Project description:KPC mice on ketogenic diet versus standard chow diet

| PRJNA961745 | ENA

Myocardial expression data from ketogenic diet-fed mice

Project description:Specific pathogen free wild-type C57Bl/6 male mice fed ketogenic diet (Bio-Serv AIN-76-A) for 4 weeks Keywords: RNA Expression Array Hearts from 12 week-old mice that were maintained on a standard polysacchardide-rich chow until the age of 8 weeks, at which time they were switched to a ketogenic diet (ad libitum) and maintained for 4 additional weeks prior to collection of tissues

2010-06-16 | E-GEOD-21368 | biostudies-arrayexpress

Translation efficiency in the pancreatic tumor in response to ketogenic diet and targeting eIF4E phosphorylation

Project description:To investigate the translatome in the pancreatic tumor inresponse to ketogenidc diet and the combination of ketogenic diet with an inhibitor targeting eIF4E phosphorylation. We generated pancreatic tumor xenograftmice model, treated mice with regular chow, ketogenic diet or ketogenic diet with eFT508, an inhibitor targeting eIF4E phosphorylation. Then we performed Poly-RNAseq on the tumor isolated from mice upon different treatments.

2024-08-14 | GSE267398 | GEO

Identification of acetylated proteins in the hearts of mice fed a ketogenic diet

Project description:Diets influence metabolism and susceptibility to disease. We have previously demonstrated that a ketogenic diet alleviates cardiac pathology, with its cardioprotective effects linked to increased lysine acetylation in the heart. To identify acetylated proteins associated with this diet, we conducted a proteomic analysis using liquid chromatography-tandem mass spectrometry in the hearts of mice fed either a ketogenic diet or a normal chow diet under hypertension. We identified 966 acetylated peptides corresponding to 320 acetylated proteins in the hearts of mice fed a normal chow diet (group A), while 1597 acetylated peptides corresponding to 425 acetylated proteins were identified in the hearts of mice fed a ketogenic diet (group M).

2025-11-03 | PXD059855 | Pride

Translation efficiency in the mouse liver upon 24h chow or ketogenic diet fed

Project description:To investigate the translatome in the ketogenic diet fed condition and the role of phosphoralated eIF4E in it We performed polysome sequencing on chow fed and 24h ketogenic diet fed wild type mice and chow fed eIF4E S209A/S209A mice

2024-08-14 | GSE267336 | GEO

Transcription profiling of mouse livers from animals fed a ketogenic diet (KD), a diet high in fat and low in carbohydrates

Project description:Analysis of liver gene transcription during feeding of a ketogenic diet. Ketogenic diets may alter physiologic and metabolic profiles in a direction that favors weight loss. C57BL/6J mice were maintained for six weeks on either chow or ketogenic diet. Mice eating KD had lower weights, 90% reduction in insulin levels and increased energy expenditure compared to animals fed chow. Despite consumption of a very high fat diet serum lipids remained normal. Here we show that consumption of KD shifted liver metabolism to drastically increased fatty acid oxidation. Concurrently, expression of genes involved in fatty acid synthesis were markedly suppressed. Reference: A high fat, ketogenic diet induces a unique metabolic state in mice. Kennedy AR, Pissios P, Out H, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Liberman TA, Maratos-Flier E. in press, 2007, Am J Physiol Metab 292. Experiment Overall Design: Eight week old C57BL/6 mice were fed either chow (Labdiet 5008, Pharmserv) or KD (F3666, Bio-Serv) for six weeks. Livers were harvested in the morning in ad lib fed animals. Total RNA from 2-3 animals in each group was used for Affymetrix analysis.

2007-12-13 | E-GEOD-7699 | biostudies-arrayexpress

A high fat, ketogenic diet induces a unique metabolic state in mice.

2007-05-04 | GSE7699 | GEO

Genetic and dietary modulators of inflammation in the gastro-intestinal tract of BXD genetic reference population

Project description:Transcriptome data measured by microarray in colon of the BXD mouse genetic diversity model under a standard chow or a high fat diet at a fastd state.

2023-08-25 | GSE225791 | GEO

Genetic and dietary determinants of gut microbiome-bile acid interactions in BXD recombinant inbred mouse population

Project description:Transcriptome data measured by microarray in proximal colon of the BXD mouse genetic diversity model under a standard chow or a high fat diet at a postprandial state.

2025-11-20 | GSE272489 | GEO

Global hepatic transcript data from fed male BXD strains on chow or high fat diet

Project description:Gene expression levels assessed by microarray in liver samples collected from the BXD mouse genetic diversity model fed either a standard chow or a high fat diet at a fed state.

2022-09-27 | GSE188764 | GEO

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