Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Epigenetic regulation of embryonic skin development (H3K27me3 ChIP-Seq)

ABSTRACT: Epigenetic regulation of embryonic skin development (H3K27me3 ChIP-Seq)

PROVIDER: PRJNA944252 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR23852524.fastq.gz	Fastqsanger.gz
	SRR23852525.fastq.gz	Fastqsanger.gz
	SRR23852526.fastq.gz	Fastqsanger.gz
	SRR23852527.fastq.gz	Fastqsanger.gz
	SRR23852528.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 5

Similar Datasets

Epigenetic regulation of embryonic skin development

Project description:Epigenetic regulation of embryonic skin development

| PRJNA940706 | ENA

Epigenetic regulation of embryonic skin development (H3K27me3 ChIP-Seq)

Project description:We performed ChIP-seq for H3K27me3 using dermal fibroblasts of WT skin at E14.5 and E18.5

2023-06-15 | GSE227262 | GEO

Epigenetic regulation of embryonic skin development

Project description:We performed ChIP-seq for H3K27me3 using dermal fibroblasts of E18.5 WT and Kdm6bKO mice. Chromatin immunoprecipitation DNA-sequencing (ChIP-seq) for H3K27me3 Fibroblasts at various time points and one Kdm6bKO condition.

2023-06-15 | GSE226567 | GEO

E2F6 initiates stable epigenetic silencing of germline genes during embryonic development

Project description:In mouse development, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes, however the molecular mechanisms of this specificity remain unclear. Here we demonstrate that the transcription factor E2F6, a member of the polycomb repressive complex 1.6 (PRC1.6), is critical to target and initiate epigenetic silencing at germline genes in early embryogenesis. Genome-wide, E2F6 binds preferentially to CpG islands in embryonic cells. E2F6 cooperates with MGA to silence a subgroup of germline genes in mouse embryonic stem cells and in vivo, a function that critically depends on the E2F6 marked box domain. Inactivation of E2f6 leads to a failure to deposit CpG island DNA methylation at these genes during implantation. Furthermore, E2F6 is required to initiate epigenetic silencing in early embryonic cells but becomes dispensable for the maintenance in differentiated cells. Our findings elucidate the mechanisms of epigenetic targeting of germline genes and provide a paradigm for how transient repression signals by DNA-binding factors in early embryonic cells are translated into long term epigenetic silencing during mammalian development.

2021-04-22 | PXD023974 | Pride

Japanese quail embryonic skin samples

Project description:Japanese quail embryonic skin samples

| PRJNA487732 | ENA

scRNA-seq of embryonic skin development (developmental time series in full-thickness dorsal skin of mouse embryos)

Project description:In this study, we analysed early embryonic skin development (mus musculus; C57BL/6J) at the transcriptional level. Major questions concerned the cell type composition of early embryonic skin, and the emergence of transcriptional heterogeneity among epithelial and stromal precursor cells. Cells were isolated from embryonic dorsal skin and randomly sequenced (scRNA-Seq using 10X Genomics v2) without any cell sorting. Data from three embryonic time points (E12.5, E13.5, and E14.5) was integrated and compared to obtain a better understanding of the dynamics of early skin development.

2023-07-16 | E-MTAB-11920 | biostudies-arrayexpress

Genome-wide epigenetic reprogramming during chick embryonic development

Project description:Genome-wide epigenetic reprogramming during chick embryonic development

| PRJNA1012695 | ENA

The X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner

Project description:This SuperSeries is composed of the following subset Series: GSE39472: X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner [ChIP-Seq data] GSE39473: The X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner [Agilent array data] Refer to individual Series

2012-07-31 | E-GEOD-39222 | biostudies-arrayexpress

Epigenetic modules governing skin epidermal homeostasis [neonate skin epidermis]

Project description:Epigenetic modules governing skin epidermal homeostasis [neonate skin epidermis]

| PRJNA808402 | ENA

Polycomb complexes in skin epithelium development III

Project description:Polycomb group (PcG) proteins are essential epigenetic transcriptional regulators. Traditionally, PcG proteins function as two multi-subunit complexes, Polycomb repressive complex 1 (PRC1) and PRC2, which largely overlap in their genomic binding and cooperate to establish repressive chromatin domains demarcated by H2AK119ub and H3K27me3. Here, using the developing skin epidermis as a paradigm, we uncovered a functional redundancy between Polycomb complexes in the repression of unwanted non-lineage genes.

2022-12-31 | GSE158323 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data