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Deoxyshikonin-induced chromatin accesibility changes in porcine intestinal epithelial cells

ABSTRACT: Deoxyshikonin-induced chromatin accesibility changes in porcine intestinal epithelial cells

PROVIDER: PRJNA951452 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR24044087_1.fastq.gz	Fastqsanger.gz
	SRR24044087_2.fastq.gz	Fastqsanger.gz
	SRR24044088_1.fastq.gz	Fastqsanger.gz
	SRR24044088_2.fastq.gz	Fastqsanger.gz
	SRR24044089_1.fastq.gz	Fastqsanger.gz

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Deoxyshikonin-induced chromatin accesibility changes in porcine intestinal epithelial cells

Project description:The objectives of this study is to evaluate the chromatin accesibility changes after deoxyshikonin stimulation in porcine intestinal epithelial cells.

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Effect of antimicrobial peptide PR-39 on the gene expression of porcine intestinal epithelial cell line (IPEC-J2)

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Project description:The intestinal epithelial cell lines 1 and J2 (IPEC-1, IPEC-J2) - spontaneously immortalised cell lines from the porcine intestine - are important tools for studying intestinal function. Microarrays (GeneChip Porcine Genome Array) were used to compare the expression pattern at basal in vitro conditions. Expression analyses complemented by morphological, functional and biochemical analyses revealed that IPEC-J2 is a morphologically and functionally more differentiated cell line in comparison to IPEC-1. In addition, IPEC-2 cells are a preferential tool for in vitro studies with the focus on metabolism.

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