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RNA-seq analysis in RPMI-8402 cells after knockout of MYC and MYCN

ABSTRACT: RNA-seq analysis in RPMI-8402 cells after knockout of MYC and MYCN

PROVIDER: PRJNA970309 | ENA |

REPOSITORIES: ENA

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RNA-seq analysis in RPMI-8402 cells after knockout of MYC and MYCN

Project description:RNA-seq analysis was performed in a RPMI-8402 T-ALL cell stably expressing Cas9 aafter knockout of both MYC and MYCN

2023-08-16 | GSE231962 | GEO

RNA-seq analysis in RPMI-8402 cells after knockout of MYCN

Project description:RNA-seq analysis was performed in a RPMI-8402 T-ALL cell stably expressing Cas9 after knockout of MYCN

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RNA-seq analysis in RPMI-8402 cells after knockout of MYC

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RNA-seq analysis in RPMI-8402 cells after knockout of MYCN

Project description:RNA-seq analysis in RPMI-8402 cells after knockout of MYCN

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RNA-seq analysis in RPMI-8402 cells after knockout of MYC

Project description:RNA-seq analysis in RPMI-8402 cells after knockout of MYC

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H3K27ac Hi-ChIP analysis in Jurkat and RPMI-8402 T-ALL cells

Project description:H3K27ac Hi-ChIP analysis was performed in Jurkat and RPMI-8402 stably expressing dCAR9-KRAB after treatment with DMSO (Control) or Doxycycline to induce sgRNA expression to block MYCN enhnacer region

2023-08-16 | GSE231957 | GEO

Genome wide analysis of binding regions for MYC, MYCN and various histone modifications using Cut&Run

Project description:Cut&Run analysis was performed in RPMI-8402 cells to analyze binding regions of MYC, MYCN and various histone modifications in normal culture conditions

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ATAC-seq analysis for Jurkat nd RPMI-8402 T-ALL cells

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TAL1 complex in human T-cell acute lymphoblastic leukemia (RPMI-8402)

2012-07-09 | GSE39179 | GEO

TAL1 complex in human T-cell acute lymphoblastic leukemia (RPMI-8402)

Project description:The oncogenic transcription factor TAL1/SCL is aberrantly overexpressed in over 40% of cases of T-cell acute lymphoblastic leukemia (T-ALL), emphasizing the importance of the TAL1-regulated transcriptional program in the molecular pathogenesis of T-ALL. Here we identify regions occupied by TAL1 and its regulatory partners HEB, E2A, and GATA3 in a T-ALL cell line (RPMI-8402). Human T-ALL cells were cross-linked with formaldehyde for 20 min. DNA was enriched by chromatin immunoprecipitation (ChIP) and analyzed by Solexa sequencing. A sample of whole cell extract (WCE) was sequenced and used as the background to determine enrichment. ChIP was performed using an antibody against total TAL1 (Santa Cruz SC-12984), TCF12/HEB (Santa Cruz SC-357),TCF3/E2A (Santa Cruz SC-349X), and GATA3 (Santa Cruz SC-22206).

2012-07-09 | E-GEOD-39179 | biostudies-arrayexpress

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